Topaz 100 Tablet

Topaz 100 Tablet is a prescription medicine that contains 100 mg of topiramate in each tablet. It belongs to the anti-convulsant class and is used to help control certain seizure disorders, and in some patients it may also be used to help prevent migraine headaches when prescribed by a doctor. Topaz 100 Tablet is the stronger tablet strength sold under this name, so it is meant for patients whose doctor has already assessed their dose needs. Because it is an oral tablet made by Intas Pharmaceuticals Ltd., it is taken by mouth with water as directed.

How it works: Topiramate helps calm overactive nerve signals in the brain, which can reduce the chance of seizures. In tablet form, Topaz 100 Tablet delivers a measured oral dose that your body absorbs after swallowing.

Topaz 100 Tablet provides 100 mg of topiramate in a single tablet, which is a relatively higher strength compared with lower-dose topiramate tablets. Doctors may choose this strength when a patient has already been titrated upward, needs a simpler tablet schedule, or requires a maintenance dose that is not easily reached with smaller strengths alone. It is not usually the first dose for most people, since topiramate is often started low and increased gradually to reduce side effects.

• Adjunct or monotherapy for certain seizure types
• Prevention of migraine headaches
• Long-term seizure control as prescribed by a specialist
• Maintenance therapy after dose titration

• Swallow Topaz 100 Tablet whole with a glass of water unless your doctor gives different instructions.
• Take it at the same time each day to help keep a steady level in your body.
• It can be taken with or without food, but taking it the same way each day helps consistency.
• Do not crush or chew the tablet unless your pharmacist or doctor specifically says it is okay.
• Drink enough fluids during treatment, unless your doctor has told you to limit fluids.
• If you miss a dose, take it when you remember unless it is close to the next dose; do not double up.

Each Topaz 100 Tablet contains 100 mg of topiramate. The number of tablets taken per day depends on the condition being treated, your age, kidney function, and how you responded to lower doses first. Your doctor decides the exact schedule; do not change the dose on your own, and do not exceed the daily amount prescribed for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Topiramate may include:

• Tingling in the hands or feet
• Drowsiness or tiredness
• Dizziness
• Loss of appetite
• Weight loss
• Trouble concentrating or slowed thinking, which can be more noticeable at 100 mg tablets
• Taste changes

• Topaz 100 Tablet is a higher-strength tablet, so dose changes should be made only by a doctor to avoid too much topiramate at once.
• Do not stop taking it suddenly unless your prescriber tells you to, because abrupt stopping can worsen seizures.
• Avoid or limit alcohol because it can increase dizziness, sleepiness, and trouble thinking.
• Use caution when driving or operating machinery until you know how Topaz 100 Tablet affects you.
• Tell your doctor if you have kidney disease, a history of kidney stones, glaucoma, depression, or a history of metabolic acidosis.
• Stay well hydrated unless instructed otherwise, because topiramate can increase the risk of kidney stones.
• Tell your clinician if you are pregnant, planning pregnancy, or breastfeeding, since topiramate may require special risk-benefit review.

• Other medicines that can cause sleepiness or dizziness, including alcohol, opioids, and some anxiety medicines
• Carbonic anhydrase inhibitors such as acetazolamide, which can raise the risk of acidosis or kidney stones
• Other anti-seizure medicines, which may require dose adjustment
• Estrogen-containing birth control, which may be less effective at higher topiramate exposures
• Metformin, which may need monitoring if used together

Store Topaz 100 Tablet at room temperature in the original strip/box of 10 tablets, away from moisture, heat, and direct light.