Oestrogel 2.5 g/1.5 mg Gel

Oestrogel 2.5 g/1.5 mg Gel is a transdermal estradiol medicine used in women’s health. Each bottle contains 2.5 g of gel delivering 1.5 mg of estradiol, a form of estrogen. It belongs to the hormone replacement therapy (HRT) class and is prescribed to help relieve symptoms of estrogen deficiency, especially menopausal symptoms. Because it is absorbed through the skin, Oestrogel 2.5 g/1.5 mg Gel provides systemic estrogen support without swallowing a tablet.

How it works: Estradiol replaces estrogen that the body is making less of, which can help reduce hot flashes, vaginal dryness, and other menopause-related symptoms. As a gel, it is applied to the skin so estradiol passes through the skin into the bloodstream for whole-body effect.

Oestrogel 2.5 g/1.5 mg Gel is a specific bottle strength that may be chosen when a doctor wants a measured transdermal estradiol dose that can be adjusted to the patient’s needs. Since there are no other Oestrogel strengths or forms listed here, this product should be understood as one exact prescribed option rather than a starter dose for everyone. The gel format can be preferable for people who want skin absorption and a form that may be easier to tailor than some oral estrogen products.

• Relief of menopausal hot flashes
• Reduction of night sweats
• Treatment of estrogen-deficiency symptoms
• Support for vaginal or urogenital menopause symptoms when prescribed
• Hormone replacement therapy under a doctor’s supervision

• Apply the gel to clean, dry, unbroken skin exactly as prescribed by your doctor.
• Use the measured amount from the Oestrogel 2.5 g/1.5 mg bottle; do not guess or use extra gel.
• Spread it over a large area such as the arm, shoulder, or thigh if your prescriber instructs.
• Let the gel dry before dressing and wash your hands after applying.
• Avoid washing the application area, swimming, or heavy sweating for a while after application so the dose can absorb properly.
• Use it at the same time each day if your doctor has given a daily schedule.

Each Oestrogel 2.5 g/1.5 mg Gel bottle provides 2.5 g of gel containing 1.5 mg of estradiol. How often it is used depends on the treatment plan your doctor chooses; some patients use it once daily, while others may need a different schedule based on symptoms and response. The maximum daily amount should be set by the prescriber, and you should not increase the dose on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Estradiol may include:

• Skin irritation, redness, or itching where Oestrogel 2.5 g/1.5 mg Gel is applied
• Headache
• Breast tenderness
• Nausea
• Bloating
• Mood changes
• Spotting or irregular vaginal bleeding

• Do not use Oestrogel 2.5 g/1.5 mg Gel if you have unexplained vaginal bleeding unless your doctor has evaluated it.
• Tell your doctor if you have a history of blood clots, stroke, heart disease, liver disease, breast cancer, or estrogen-sensitive cancer.
• Use caution if you smoke, because smoking can raise estrogen-related cardiovascular risks.
• This gel is for skin use only; do not apply it to broken, irritated, or infected skin.
• Avoid letting the gel transfer to other people, especially children or pregnant women, until it has fully dried.
• Alcohol does not directly treat menopause symptoms and may worsen dizziness or flushing in some patients.
• Do not drive or use machinery if you feel dizzy or unwell after applying it.

• Other estrogen or hormone products, which can increase hormone exposure
• Certain seizure medicines such as carbamazepine or phenytoin, which may change estrogen levels
• Rifampin and similar antibiotics, which can reduce estrogen effectiveness
• St. John’s wort, which may lower hormone levels
• Blood thinners such as warfarin, which may be affected by estrogen therapy

Store Oestrogel 2.5 g/1.5 mg Gel at room temperature in its original strip/box of 10 bottles, away from heat, moisture, and direct sunlight.