Co-Diovan 160/25 Tablet

Co-Diovan 160/25 Tablet is a prescription blood pressure medicine that combines valsartan 160 mg and hydrochlorothiazide 25 mg in each tablet. Valsartan is an angiotensin receptor blocker (ARB), and hydrochlorothiazide is a thiazide diuretic, so this combination helps lower high blood pressure by relaxing blood vessels and helping the body remove extra salt and water. It is used to treat hypertension in adults when one medicine alone is not enough. Lowering blood pressure can help reduce the risk of stroke, heart attack, and kidney problems over time.

How it works: In this tablet, valsartan blocks a hormone signal that tightens blood vessels, which helps blood flow more easily. Hydrochlorothiazide helps the kidneys remove extra salt and water, lowering blood volume and reducing pressure on the blood vessels.

Co-Diovan 160/25 Tablet is a higher-strength combination than Co-Diovan 80/12.5 Tablet, so it is usually chosen for people who need stronger blood pressure control after a doctor has assessed their response to a lower dose. Because it contains 25 mg of hydrochlorothiazide, it may cause more urination, dizziness, or low blood pressure than the lower-strength tablet, especially when first started or when the dose is increased. A clinician may choose this strength when the 80/12.5 tablet is not enough to control blood pressure on its own.

• Treatment of high blood pressure in adults
• May be used when one medicine is not enough
• Helps lower risk of stroke and heart attack linked to hypertension
• Used as a prescription combination therapy for blood pressure control

• Swallow Co-Diovan 160/25 Tablet whole with water.
• Take it at the same time each day to help you remember.
• You may take it with or without food.
• Because it contains hydrochlorothiazide, it may make you urinate more; morning dosing is often preferred unless your doctor tells you otherwise.
• Do not split, crush, or chew the tablet unless your pharmacist or doctor says it is okay.
• Stand up slowly from sitting or lying down, especially when you first start this strength.

Each Co-Diovan 160/25 Tablet provides valsartan 160 mg plus hydrochlorothiazide 25 mg. Your doctor decides how often you take it based on your blood pressure, kidney function, and how you respond to treatment; for many adults, it is taken once daily. Do not take more than prescribed, because this strength already contains a relatively higher diuretic dose and can increase the risk of low blood pressure, dehydration, or electrolyte problems.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Valsartan + Hydrochlorothiazide may include:

• Dizziness or lightheadedness, especially when standing up
• Increased urination
• Headache
• Fatigue or weakness
• Nausea
• Low blood pressure symptoms
• Muscle cramps or thirst, which may be more noticeable with the 25 mg hydrochlorothiazide strength

• Do not use during pregnancy; valsartan can harm an unborn baby.
• Tell your doctor if you have kidney disease, liver disease, diabetes, gout, or a history of dehydration.
• This 25 mg hydrochlorothiazide strength can lower potassium and sodium and may raise uric acid or blood sugar.
• Use caution with alcohol, since it can worsen dizziness and low blood pressure.
• Be careful driving or using machinery until you know how Co-Diovan 160/25 Tablet affects you.
• Avoid becoming dehydrated from vomiting, diarrhea, heavy sweating, or very low salt intake.
• Tell your clinician if you have had angioedema or are taking other blood pressure medicines.

• NSAIDs such as ibuprofen or naproxen may reduce blood pressure control and affect kidney function.
• Potassium supplements or salt substitutes containing potassium may raise potassium too much.
• Lithium levels can increase and become toxic.
• Other blood pressure medicines, especially ACE inhibitors or other diuretics, can increase dizziness or kidney problems.
• Digoxin or diabetes medicines may require monitoring depending on your overall health and labs.

Store Co-Diovan 160/25 Tablet at room temperature in the original strip/box, away from moisture, heat, and direct light.