Tamdosin D Tablet MR

Tamdosin D Tablet MR is a prescription tablet that contains tamsulosin and dutasteride in each tablet as labelled. It belongs to the alpha blocker combination category and is used to treat the urinary symptoms of benign prostatic hyperplasia (BPH), also called an enlarged prostate. This medicine helps improve urine flow and may also help reduce prostate size over time. Tamdosin D Tablet MR is not used to treat prostate cancer.

How it works: Tamsulosin relaxes the muscles in the prostate and bladder neck so urine can pass more easily. Dutasteride lowers the body’s production of dihydrotestosterone (DHT), which can shrink an enlarged prostate over time; as a tablet, Tamdosin D Tablet MR delivers both medicines in one oral dose.

Tamdosin D Tablet MR is a combination tablet that is generally chosen when a doctor wants both faster symptom relief from tamsulosin and longer-term prostate shrinkage from dutasteride. Because it is the labeled-strength MR tablet, it is intended for people whose prescriber has already decided this combination and dose are appropriate; it is not a lower starter strength that is meant to be split or adjusted on your own.

• Benign prostatic hyperplasia (BPH)
• Weak urine stream
• Trouble starting urination
• Frequent or urgent urination
• Nighttime urination caused by enlarged prostate

• Swallow Tamdosin D Tablet MR whole with water; do not crush, chew, or split it unless your prescriber says otherwise.
• Take it at the same time each day so your body gets used to the schedule.
• You may take it with or without food unless your doctor gives different instructions.
• Stand up slowly after taking it, especially when you first start treatment, because it can lower blood pressure and cause dizziness.
• If you miss a dose, do not double up; take the next dose at the usual time.
• Follow the exact timing your doctor gives you, since this is a prescription combination tablet and not for occasional use.

Tamdosin D Tablet MR provides the labeled amount of tamsulosin plus dutasteride in each tablet. The usual dose is one tablet once daily, but your doctor decides whether this strength is appropriate for you and may adjust based on your symptoms and tolerability. Do not take more than one tablet in 24 hours unless specifically instructed by your prescriber.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Tamsulosin + Dutasteride may include:

• Dizziness, especially when standing up
• Lightheadedness or faint feeling
• Runny or stuffy nose
• Ejaculation changes or reduced semen amount
• Headache
• Tiredness
• Stomach upset

• This is a higher-strength prescription combination for men with BPH and should be used only if a doctor has assessed you.
• It can cause dizziness or fainting, so be careful when driving, using machinery, or standing up quickly.
• Avoid taking it with other alpha blockers unless your doctor specifically approves.
• Tell your doctor if you have low blood pressure, liver disease, or a history of fainting.
• Tell your eye surgeon before cataract or glaucoma surgery because tamsulosin can affect the procedure.
• Use caution with alcohol because it can worsen dizziness or lightheadedness.
• Women, children, and anyone who is pregnant should not handle leaking or broken tablets because dutasteride can be absorbed through the skin.

• Other alpha blockers such as doxazosin or alfuzosin
• Blood pressure medicines that can increase dizziness or fainting
• PDE-5 inhibitors such as sildenafil, tadalafil, or vardenafil
• Strong CYP3A4 inhibitors such as ketoconazole or ritonavir
• Warfarin or other medicines where your doctor wants closer monitoring

Store Tamdosin D Tablet MR in the original strip or box at room temperature, away from moisture, heat, and direct light.