Donamem 10 mg Tablet

Donamem 10 mg Tablet is a prescription medicine that combines donepezil 10 mg and memantine 10 mg in each tablet. It belongs to the anti-dementia medicines used to help manage symptoms of Alzheimer’s disease, especially memory, thinking, and daily functioning. Donamem 10 mg Tablet is not a cure for Alzheimer’s, but it may help slow worsening of symptoms in some people. It is made by Sun Pharmaceutical Industries Ltd. and comes as a strip/box of 10 tablets.

How it works: Donepezil helps increase a brain chemical called acetylcholine, which supports memory and learning. Memantine helps balance another brain chemical, glutamate, which may protect brain cells from overactivity, and the tablet form makes it easy to take the prescribed combination in one dose.

Donamem 10 mg Tablet is a fixed-dose tablet that contains both donepezil and memantine at the 10 mg strength, so it is generally suited to patients whose doctor has already decided they need this combined dose rather than a lower-strength start. Compared with lower-strength tablets, Donamem 10 mg Tablet is not meant for casual initiation or self-adjustment; it is typically chosen when a clinician wants a steady maintenance-strength combination in one tablet. Because it is a higher-strength Alzheimer’s medicine tablet, it should be used only under medical supervision.

• Alzheimer’s disease
• Memory and thinking problems related to dementia
• Support for daily function in moderate to severe Alzheimer’s disease
• Combination therapy when a doctor wants donepezil and memantine together

• Swallow Donamem 10 mg Tablet whole with water unless your doctor gives different instructions.
• Take it at the same time each day to keep a steady effect.
• You may take it with or without food if your prescriber allows; food can help if it upsets your stomach.
• Do not crush, split, or chew the tablet unless your pharmacist or doctor says the tablet can be altered.
• If a dose is missed, do not double up; take the next dose at the usual time.
• Do not stop taking Donamem 10 mg Tablet suddenly without medical advice.

Each Donamem 10 mg Tablet provides donepezil 10 mg plus memantine 10 mg. The usual schedule may be once daily or as your doctor directs, and the exact dose and timing depend on the patient’s condition and tolerance. Do not take more than the amount prescribed, and your doctor decides whether this strength is the right maintenance dose for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Donepezil + Memantine may include:

• nausea
• vomiting
• diarrhea
• loss of appetite
• dizziness
• headache
• sleep disturbance or vivid dreams

• Use caution if you have heart rhythm problems, a history of fainting, or slow pulse.
• Tell your doctor if you have asthma, COPD, stomach ulcers, or a history of seizures.
• This 10 mg combination strength may be harder to tolerate if you are sensitive to stomach upset or dizziness.
• Be careful with driving or using machinery until you know how Donamem 10 mg Tablet affects you.
• Avoid alcohol unless your doctor says it is okay, because it can worsen dizziness or confusion.
• Do not use this medicine without medical advice if you have serious kidney or liver disease.
• Tell your clinician about all medicines you take, especially heart medicines and other drugs that affect the brain.

• Other cholinesterase inhibitors
• Anticholinergic medicines
• Medicines that slow the heart, such as beta-blockers
• Ketamine or other NMDA-affecting medicines
• Alcohol and sedating medicines

Store Donamem 10 mg Tablet in its original strip/box at room temperature, away from moisture, heat, and children.