Combantrin A 400 mg Tablet

Combantrin A 400 mg Tablet is a prescription anthelmintic medicine containing albendazole 400 mg in each tablet. It is used to treat worm infections caused by susceptible parasites, including several intestinal and tissue worm infections. As an anti-worm tablet, Combantrin A 400 mg Tablet works by stopping worms from absorbing the nutrients they need to survive. Your doctor may choose this strength when a single 400 mg dose or a 400 mg tablet is appropriate for the infection being treated.

How it works: Albendazole in Combantrin A 400 mg Tablet blocks the worms from using glucose and forming essential structures they need to live. This weakens and kills the parasites, and the tablet form is swallowed so the medicine can be absorbed and reach the infection site.

The 400 mg tablet is a full-strength albendazole tablet, so it is not a low-dose starter form. It may be used when a clinician wants the standard adult tablet strength for a confirmed worm infection, rather than a smaller or repeated lower-dose regimen. Because Combantrin A 400 mg Tablet is a higher-strength tablet, it should be taken only as directed by a doctor who has assessed the infection and the correct dosing schedule.

• Treatment of intestinal worm infections
• Treatment of certain tissue worm infections
• Control of susceptible helminth infections
• Parasite treatment as prescribed by a doctor

• Swallow Combantrin A 400 mg Tablet with water unless your doctor gives different instructions.
• Take it with food if your prescriber or pharmacist tells you to do so, since food can improve absorption for some parasitic infections.
• Do not crush or split the tablet unless your healthcare professional specifically says it is okay.
• Take the dose exactly on the schedule prescribed; some infections need one dose, while others need repeated doses.
• If your doctor advises repeat treatment for household contacts or follow-up testing, follow that plan carefully.
• Complete the full course if more than one tablet or dose is prescribed, even if you feel better.

Each Combantrin A 400 mg Tablet provides 400 mg of albendazole per tablet. Depending on the infection, a doctor may prescribe one tablet as a single dose or a repeated schedule; the maximum number of tablets per day depends on the specific diagnosis and should be set by the prescriber. Do not self-adjust the dose, because the correct use of this 400 mg strength varies by parasite type, body weight, and whether follow-up treatment is needed.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Albendazole may include:

• Abdominal pain or cramping
• Nausea
• Vomiting
• Diarrhea
• Headache
• Dizziness
• Mild liver test changes

• Use Combantrin A 400 mg Tablet only under medical supervision, especially because this is a higher-strength albendazole tablet.
• Tell your doctor if you are pregnant, may become pregnant, or are breastfeeding, because albendazole may not be appropriate in pregnancy.
• Your prescriber may order liver tests or blood counts during treatment, especially with longer courses.
• Use caution if you have liver disease, because albendazole can affect the liver and may need dose adjustment or monitoring.
• Tell your doctor about a history of bone marrow problems or low blood counts before starting treatment.
• Avoid driving or hazardous activity if this tablet makes you dizzy or unwell.
• Do not drink alcohol heavily during treatment, since liver side effects can be harder to monitor.

• Dexamethasone
• Cimetidine
• Praziquantel
• Carbamazepine or phenytoin
• Ritonavir

Store Combantrin A 400 mg Tablet in its original strip at room temperature, away from moisture, heat, and direct light.