Nolvadex 10 mg Tablets

Nolvadex 10 mg Tablets contain tamoxifen 10 mg in each tablet. It is a prescription anti-cancer medicine in the selective estrogen receptor modulator (SERM) class, manufactured by AstraZeneca, India. Nolvadex 10 mg Tablets are used to treat and help prevent certain estrogen receptor-positive breast cancers in adults. Because it is a tablet strength of tamoxifen, the exact dose and schedule are chosen by a doctor based on the cancer type, treatment goal, and patient response.

How it works: Tamoxifen in Nolvadex 10 mg Tablets blocks estrogen from attaching to estrogen receptors in breast tissue, which can slow or stop the growth of hormone-sensitive cancer cells. As an oral tablet, it is taken by mouth and absorbed into the body to provide ongoing anti-estrogen activity.

Nolvadex 10 mg Tablets is a lower tablet strength that allows more flexible dose adjustment than higher-strength tamoxifen products, and it may be used when a doctor wants smaller, carefully titrated doses. It is not a starter or self-directed dose; some people may take one or more Nolvadex 10 mg Tablets per day depending on the prescribed regimen.

• Treatment of estrogen receptor-positive breast cancer
• Adjuvant therapy after breast cancer surgery
• Reduction of breast cancer recurrence risk
• Treatment of metastatic breast cancer
• Breast cancer risk reduction in selected patients

• Swallow Nolvadex 10 mg Tablets whole with a glass of water.
• Take it exactly as prescribed; do not change the number of tablets on your own.
• It may be taken with or without food if your prescriber does not advise otherwise.
• Try to take it at the same time each day to help you remember.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Do not crush or chew the tablet unless your doctor or pharmacist tells you to.

Each Nolvadex 10 mg Tablet provides 10 mg of tamoxifen. Depending on your diagnosis, a doctor may prescribe it once or more than once daily, and the total daily dose is set by the prescriber; do not exceed the prescribed amount, even though the tablet is only 10 mg. Because this is a cancer medicine, the dosing schedule and maximum daily dose are individualized and should be followed exactly.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Tamoxifen may include:

• Hot flashes
• Nausea
• Fatigue
• Headache
• Menstrual changes
• Mild swelling or fluid retention
• Mood changes

• Nolvadex 10 mg Tablets is a prescription anti-cancer medicine and should only be used under oncology or specialist supervision.
• Tell your doctor if you have a history of blood clots, stroke, heart disease, liver disease, or high triglycerides before starting tamoxifen.
• Report any vaginal bleeding, pelvic pain, or new breast symptoms promptly, especially if you are postmenopausal.
• This medicine can affect fertility and menstrual cycles; discuss pregnancy prevention and family planning with your doctor.
• Do not use during pregnancy unless specifically directed, because tamoxifen can harm an unborn baby.
• Use caution with driving or activities requiring alertness if you feel dizzy, tired, or have vision changes.
• Avoid smoking if possible, since smoking can further increase clot risk in some patients.

• Warfarin and other blood thinners may interact and increase bleeding risk.
• Certain antidepressants that affect CYP2D6, such as paroxetine or fluoxetine, can reduce tamoxifen activation.
• Rifampin and some seizure medicines can lower tamoxifen levels.
• Estrogen-containing medicines, including some hormone therapies, may reduce the effect of tamoxifen.
• Tell your prescriber about all prescription, OTC, and herbal products, including supplements such as St. John’s wort.

Store Nolvadex 10 mg Tablets at room temperature in the original strip/box, away from moisture, heat, and direct light.