Mezaril 400 mg Tablet SR

Mezaril 400 mg Tablet SR is a sustained-release carbamazepine tablet used to help control certain seizure disorders. Each tablet contains 400 mg of carbamazepine, an anti-convulsant medicine. It may also be prescribed for other nerve-related or mood-related conditions when a doctor decides it is appropriate. Because this is a sustained-release tablet, it is designed to release medicine gradually over time.

How it works: Carbamazepine calms overactive nerve signals in the brain by reducing the firing of certain nerve cells. In the Mezaril 400 mg Tablet SR form, the sustained-release tablet lets the medicine enter the body more gradually, which may help maintain more even coverage between doses.

Mezaril 400 mg Tablet SR is a higher-strength tablet, so it is usually chosen for people who have already been assessed by a doctor and need a larger carbamazepine dose in fewer tablets. Compared with lower strengths, the 400 mg SR form may simplify dosing, but it is not meant for everyone starting treatment. The sustained-release design helps provide steadier blood levels over the day.

• Seizure control in epilepsy
• Trigeminal neuralgia
• Other nerve pain conditions prescribed by a doctor
• Bipolar disorder maintenance when appropriate

• Swallow Mezaril 400 mg Tablet SR whole with water; do not crush, chew, or split the sustained-release tablet unless your doctor says it is okay.
• Take it at the same times each day to keep blood levels steady.
• It can be taken with food or after meals if it upsets your stomach.
• Do not suddenly stop taking Mezaril 400 mg Tablet SR, because seizures or symptoms may worsen.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose; do not double up.

Each Mezaril 400 mg Tablet SR provides 400 mg of carbamazepine, so it is a relatively high single tablet strength. How often it is taken and the total daily dose vary widely; some people may take it once or more than once daily, and the maximum amount per day is set by the prescriber based on the condition being treated, response, and blood test results. Your doctor chooses the exact schedule for this strength because carbamazepine dosing must be individualized.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Carbamazepine may include:

• Drowsiness
• Dizziness
• Nausea
• Vomiting
• Blurred or double vision
• Unsteady walking or poor coordination
• Headache

• Mezaril 400 mg Tablet SR is a higher-strength tablet, so follow the prescribed dose exactly and do not use extra tablets to catch up.
• Avoid alcohol because it can increase drowsiness, dizziness, and poor coordination.
• Do not drive or operate machinery until you know how Mezaril 400 mg Tablet SR affects you.
• Tell your doctor if you have liver disease, kidney disease, heart disease, glaucoma, or a history of blood problems.
• This medicine can reduce the effectiveness of hormonal birth control and may require backup contraception.
• Carbamazepine can cause serious skin reactions, especially in some people with specific genetic risk factors.
• Regular blood tests may be needed to monitor blood counts, liver function, and drug levels.

• Warfarin
• Hormonal birth control pills, patches, or rings
• Certain antibiotics and antifungal medicines
• Other seizure medicines
• Alcohol

Store Mezaril 400 mg Tablet SR in its original strip or box at room temperature, away from moisture, heat, and direct light.