Ondem 8 mg Tablet

Ondem 8 mg Tablet is a prescription antiemetic tablet that contains 8 mg of ondansetron in each tablet. Ondansetron is a serotonin 5-HT3 receptor blocker used to help prevent and treat nausea and vomiting. Ondem 8 mg Tablet may be used for nausea and vomiting related to chemotherapy, radiation therapy, surgery, or other causes when a doctor decides this strength is appropriate. Each box contains a strip of 10 tablets from Alkem Laboratories, India.

How it works: Ondansetron in Ondem 8 mg Tablet blocks serotonin signals that can trigger the nausea-and-vomiting reflex in the brain and gut. By reducing those signals, the tablet helps prevent or lessen vomiting episodes. Because it is a tablet, Ondem 8 mg Tablet is swallowed and absorbed through the digestive tract to start working systemically after taking it.

Ondem 8 mg Tablet is a higher-strength tablet, so it is usually chosen for patients who need more ondansetron per dose than lower-strength tablets can provide. Because this is an 8 mg strength, it should be used only when a clinician has assessed that this dose fits the patient’s needs and the timing of treatment.

• Prevention of chemotherapy-related nausea and vomiting
• Prevention of radiation-related nausea and vomiting
• Prevention of postoperative nausea and vomiting
• Treatment of nausea and vomiting when prescribed by a doctor

• Swallow Ondem 8 mg Tablet whole with water unless your doctor gives different instructions.
• Take it exactly at the time prescribed, which may be before chemotherapy, radiation, surgery, or another nausea-triggering event.
• This is a swallowed tablet, not a chewable or dissolvable form.
• It can be taken with or without food; if it upsets your stomach, taking it with a light meal may help.
• Do not split, crush, or chew the tablet unless a pharmacist or doctor specifically tells you to.
• If you miss a dose for a scheduled treatment plan, contact your prescriber or pharmacist for guidance rather than doubling up.

Each Ondem 8 mg Tablet provides 8 mg of ondansetron per tablet. The doctor decides the schedule based on the reason for treatment and the patient’s medical history; some people may take it once before a trigger, while others may take it at intervals during a treatment plan. Do not take more often or in larger amounts than prescribed, because the daily maximum depends on the indication and the individual dosing plan.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Ondansetron may include:

• Headache
• Constipation
• Dizziness
• Fatigue
• Flushing
• Diarrhea
• Mild lightheadedness

• Ondem 8 mg Tablet is a higher-strength ondansetron tablet, so it should be used only as directed by a clinician familiar with the treatment plan.
• Tell your doctor if you have heart disease, a history of long QT syndrome, low potassium or magnesium, or a slow or irregular heartbeat.
• Use extra caution if you take other medicines that can affect heart rhythm or serotonin levels.
• Alcohol can worsen dizziness or drowsiness, so it is best to avoid it unless your clinician says it is okay.
• Do not drive or operate machinery if the tablet makes you dizzy or sleepy.
• Tell your doctor if you are pregnant, breastfeeding, or have liver problems before using this strength.
• This tablet is not meant to treat nausea from all causes, so persistent vomiting needs medical review.

• Other medicines that may prolong the QT interval, including some antiarrhythmics, antipsychotics, and certain antibiotics
• Serotonergic medicines such as SSRIs, SNRIs, MAOIs, triptans, or tramadol
• Apomorphine
• Some chemotherapy medicines and other anti-cancer regimens that require dosing coordination

Store Ondem 8 mg Tablet in its original strip at room temperature, away from excess heat, moisture, and direct light.