Entacom 200 mg Tablet

Entacom 200 mg Tablet is a prescription medicine that contains 200 mg of entacapone in each tablet. It belongs to the anti-Parkinsonian drug class and is used along with levodopa/carbidopa to help control symptoms of Parkinson’s disease, especially when “wearing off” happens before the next dose. Entacom 200 mg Tablet is not used on its own for Parkinson’s symptoms. It is taken by mouth as a tablet and should be used only when a clinician has decided that this strength is appropriate.

How it works: Entacapone helps levodopa stay active in the body longer by blocking an enzyme called COMT that breaks it down. As a tablet, Entacom 200 mg Tablet is taken with levodopa/carbidopa so more levodopa can reach the brain and work for a longer time.

Each Entacom 200 mg Tablet provides the full standard tablet strength of entacapone, so it is suited to patients whose doctor wants this exact 200 mg dose rather than a lower strength. Because it is a higher-strength, prescription-only tablet, it is typically chosen when a patient needs the established per-dose amount used with levodopa/carbidopa, not when starting Parkinson’s treatment from scratch. A doctor may choose Entacom 200 mg Tablet to fit the timing of levodopa doses and to reduce end-of-dose symptom return.

• Parkinson’s disease treatment with levodopa/carbidopa
• Helps reduce “wearing-off” between levodopa doses
• May improve time spent with better symptom control
• Adjunct therapy for motor fluctuations

• Swallow Entacom 200 mg Tablet whole with water; do not crush or chew unless your prescriber tells you otherwise.
• Take it exactly with each levodopa/carbidopa dose as directed, because timing matters for this medicine.
• You can take it with or without food, but follow the same routine each day if possible.
• Do not take extra tablets to make up for a missed dose unless your doctor specifically instructs you to do so.
• If your urine becomes more orange-brown, that can happen with entacapone and is usually harmless.
• If you notice nausea or dizziness after starting Entacom 200 mg Tablet, let your prescriber know; the timing with levodopa may need review.

Each Entacom 200 mg Tablet contains 200 mg of entacapone, which is the usual tablet strength used with levodopa/carbidopa. The doctor decides how often it should be taken; it is commonly used with each levodopa dose, and the maximum recommended total is 1,600 mg per day. Do not change the schedule or exceed the daily maximum without medical advice.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Entacapone may include:

• Diarrhea
• Nausea
• Dizziness
• Orange-brown urine discoloration
• Abdominal pain
• Dry mouth
• Increased sweating

• Entacom 200 mg Tablet should be used with levodopa/carbidopa, not as a stand-alone Parkinson’s treatment.
• Tell your doctor if you have liver disease, because entacapone may not be appropriate in some liver conditions.
• This medicine can increase levodopa-related side effects such as dizziness, low blood pressure, or involuntary movements.
• Use caution when driving or standing up quickly, especially when first starting treatment or after dose changes.
• Avoid alcohol if it makes you more dizzy or drowsy while taking this medicine.
• Tell your prescriber about a history of mental health symptoms, hallucinations, or severe diarrhea.
• If you have a muscle disorder called rhabdomyolysis symptoms or severe weakness, seek help promptly.

• Levodopa/carbidopa products, because Entacom 200 mg Tablet is meant to be used with them and may require dose adjustment.
• MAO inhibitors, especially nonselective MAO inhibitors, due to interaction risk with Parkinson’s medicines.
• Drugs that can lower blood pressure, because dizziness or fainting may be more likely.
• Iron supplements, which may affect how some patients take their Parkinson’s medicines and should be reviewed with a doctor.
• Other medicines that cause drowsiness or confusion, which can increase fall and mental-status risk.

Store Entacom 200 mg Tablet in the original strip/box at room temperature, away from moisture and heat, and keep it out of reach of children.