Hepcinat LP Tablet

Hepcinat LP Tablet is an antiviral medicine that contains ledipasvir and sofosbuvir in each tablet, as labelled by the manufacturer. It belongs to the direct-acting antiviral class and is used to treat chronic hepatitis C infection in appropriate patients. Hepcinat LP Tablet is a tablet dosage form made by Natco Pharma, India, and it is taken as part of a prescribed hepatitis C treatment plan.

How it works: Ledipasvir blocks a hepatitis C protein that the virus needs to build new virus particles, while sofosbuvir stops the virus from copying its genetic material. Taken as a tablet, Hepcinat LP Tablet helps lower the amount of hepatitis C virus in the body so the infection can be cleared with the full prescribed course.

Hepcinat LP Tablet is a fixed-dose combination tablet, so each tablet already contains the full labelled amounts of ledipasvir and sofosbuvir in one dose. Because there are no other strengths or forms listed for this brand, this product fits the standard tablet-based regimen a doctor selects for patients who are appropriate for ledipasvir/sofosbuvir treatment. A clinician may choose this tablet when a once-daily oral regimen is suitable and when the patient has been assessed for liver status, other medicines, and hepatitis C genotype.

• Chronic hepatitis C infection
• Combination antiviral therapy for HCV
• Treatment in patients selected by a healthcare professional
• Used with or without other prescribed hepatitis C medicines

• Swallow Hepcinat LP Tablet whole with water; do not crush, split, or chew unless your prescriber tells you to.
• Take it at the same time every day to keep a steady level of medicine in your body.
• It may be taken with or without food, unless your doctor gives different instructions.
• If you use an antacid, separate it from Hepcinat LP Tablet by the timing your clinician recommends.
• Do not take extra tablets to make up for a missed dose without following your doctor’s directions.
• Complete the full treatment course even if you feel well before it is finished.

Each Hepcinat LP Tablet provides the labelled fixed dose of ledipasvir plus sofosbuvir in one tablet. This strength is typically taken once daily, and the number of tablets per day is decided by the prescriber based on your hepatitis C type, liver condition, and other medicines; do not take more than directed, and the usual maximum is 1 tablet per day unless your doctor specifically instructs otherwise. Because this is a prescription antiviral, the exact duration and dosing schedule must be individualized by a healthcare professional.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Ledipasvir + Sofosbuvir may include:

• Headache
• Tiredness
• Nausea
• Diarrhea
• Trouble sleeping
• Feeling weak or low on energy
• Dizziness

• Use Hepcinat LP Tablet only if your doctor has confirmed it is appropriate for your hepatitis C treatment plan.
• Tell your prescriber if you have had hepatitis B, because hepatitis B can flare up during or after hepatitis C treatment.
• Tell your doctor about any heart disease or if you take medicines for abnormal heart rhythm, especially amiodarone.
• People with severe kidney disease or severe liver disease need careful medical review before using this tablet.
• Avoid alcohol or keep it strictly limited, since alcohol can worsen liver damage.
• Do not stop or start other medicines, including over-the-counter products and supplements, without checking for interactions.
• If you feel dizzy or tired, use caution when driving or operating machinery.

• Amiodarone
• Antacids containing aluminum or magnesium
• Rifampin or rifabutin
• Certain seizure medicines such as carbamazepine, phenytoin, or phenobarbital
• St. John's wort

Store Hepcinat LP Tablet in its original strip or box at room temperature, away from moisture, heat, and direct light.