Combutol 800 + 300 mg Tablet

Combutol 800 + 300 mg Tablet is a prescription combination antibiotic tablet that contains ethambutol 800 mg and isoniazid 300 mg in each tablet. It is used as part of combination treatment for tuberculosis, not as a stand-alone cure. This Combutol 800 + 300 mg Tablet is manufactured by Lupin, India and is supplied in a strip/box of 10 packs.

How it works: Ethambutol slows the growth of TB bacteria by interfering with the bacteria’s ability to build a normal cell wall. Isoniazid blocks an essential step bacteria need to make their cell wall, and this tablet form delivers both medicines together for combination TB treatment.

This Combutol 800 + 300 mg Tablet is a higher-strength tablet, so it is usually chosen for patients who need a full treatment dose and have already been assessed by a doctor. Compared with lower-strength tablets, it can reduce the number of tablets needed per dose, but it is not meant for self-starting or dose guessing. Your prescriber may select this strength to match your weight, treatment phase, and other medicines.

• Treatment of active tuberculosis as part of combination therapy
• TB infection management when a doctor prescribes ethambutol + isoniazid together
• Helps prevent TB bacteria from multiplying
• Used only with other anti-TB medicines, not alone

• Swallow the Combutol 800 + 300 mg Tablet whole with a glass of water.
• Take it exactly on the schedule your doctor gives you; do not change the dose on your own.
• If your stomach is sensitive, your doctor may tell you to take it with food; follow their instructions.
• Take it at the same time each day to help you remember doses.
• Avoid alcohol while taking this tablet, unless your doctor says otherwise.
• Do not crush or split the tablet unless your prescriber or pharmacist tells you it is appropriate.

Each Combutol 800 + 300 mg Tablet provides 800 mg of ethambutol and 300 mg of isoniazid in one tablet. The number of tablets taken and how often they are taken depends on the TB regimen, body weight, and medical history; some patients may take one dose daily, but the exact schedule must be set by the doctor. There is no fixed maximum for every patient because dosing is individualized, so never take more than prescribed.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Ethambutol + Isoniazid may include:

• Nausea
• Stomach upset
• Loss of appetite
• Dizziness
• Headache
• Tingling or numbness in the hands or feet
• Mild fatigue

• This is a higher-strength TB tablet and should only be used under a doctor’s supervision.
• Do not drink alcohol, because this combination can increase liver stress.
• Tell your doctor if you have liver disease, kidney disease, diabetes, gout, or a history of vision problems.
• Ethambutol can affect eyesight, so report any blurred vision or trouble seeing colors right away.
• Use caution when driving or operating machinery until you know how this tablet affects you.
• Tell your doctor about all other medicines and supplements, especially those that affect the liver.
• Follow the full TB treatment plan even if you start feeling better.

• Alcohol
• Rifampin and other TB medicines
• Phenytoin
• Warfarin
• Other medicines that can affect the liver

Store Combutol 800 + 300 mg Tablet in its original strip at room temperature, away from moisture, heat, and direct light.