Lopide Capsule

Lopide Capsule is a loperamide hydrochloride capsule used to help control diarrhea. Each Lopide Capsule contains loperamide as labelled on the pack, and it belongs to the antidiarrheal class called peripheral opioid receptor agonists. It works to slow the movement of the intestines so stools become less frequent and less watery. It is used for short-term relief of diarrhea when a clinician has determined it is appropriate.

How it works: Loperamide in Lopide Capsule acts on opioid receptors in the gut, not the brain, to reduce bowel contractions. By slowing intestinal movement, the capsule helps the body absorb more fluid from the stool and decreases urgency.

Lopide Capsule is the capsule form of loperamide from Makers Laboratories, while Lopide Tablet is the sibling form available in this brand. The capsule may suit adults who prefer swallowing a capsule rather than a tablet and may be chosen when a clinician wants a specific loperamide strength in this dosage form. Because this is the as-labelled capsule strength, it should only be used as directed by a doctor and should not be assumed to match a lower-strength starting dose.

• Short-term relief of diarrhea
• Reducing frequent loose stools
• Helping control urgency related to diarrhea
• Supportive treatment while fluids are replaced

• Swallow Lopide Capsule whole with water; do not crush, open, or chew it.
• Take it exactly as prescribed, often after a loose stool and then as directed by your clinician.
• Keep drinking clear fluids to prevent dehydration while using Lopide Capsule.
• Do not use more capsules than instructed, even if diarrhea continues.
• If diarrhea lasts longer than 48 hours, contact a doctor before taking more.
• This capsule is for oral use only and should not be taken for constipation or abdominal bloating.

Each Lopide Capsule provides loperamide as labelled on the pack, so the dose is fixed per capsule rather than adjustable by splitting. The number of capsules taken and how often they are taken depends on the condition being treated and the prescriber’s instructions; the total daily dose should not exceed the maximum your doctor recommends. Your doctor decides whether this strength is appropriate, especially because higher loperamide exposure can raise the risk of serious heart rhythm problems.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Loperamide may include:

• Constipation
• Abdominal discomfort or cramping
• Nausea
• Dizziness
• Drowsiness
• Dry mouth

• Do not use Lopide Capsule if you have bloody diarrhea, high fever, or suspected food poisoning unless a clinician tells you to.
• This product should be used cautiously in people with liver disease because loperamide levels can rise.
• Avoid alcohol if it makes you sleepy or lightheaded while taking Lopide Capsule.
• Use extra caution if you have a history of heart rhythm problems, low potassium or magnesium, or are taking medicines that affect the heart.
• Do not drive or operate machinery if the capsule makes you dizzy or drowsy.
• Stop and seek medical advice if diarrhea is severe, lasts more than 2 days, or signs of dehydration appear.
• Keep out of reach of children; loperamide overdose can be dangerous.

• Amiodarone and other medicines that can affect heart rhythm
• Ritonavir or cobicistat-containing antiviral medicines
• Macrolide antibiotics such as clarithromycin
• Azole antifungals such as ketoconazole
• Other medicines that slow the gut, including some opioids or anticholinergics

Store Lopide Capsule in the original strip/box at room temperature, away from moisture, heat, and out of reach of children.