Falsu LF 80 mg/480 mg Tablet

Falsu LF 80 mg/480 mg Tablet is an artemether + lumefantrine combination tablet used to treat uncomplicated malaria caused by susceptible Plasmodium parasites. Each tablet contains 80 mg of artemether and 480 mg of lumefantrine, giving a higher-strength fixed-dose antimalarial option in a tablet form. It is not used to prevent malaria or to treat severe malaria. This product should be used only when a clinician has determined it is appropriate based on the infection and the patient’s weight and history.

How it works: Artemether quickly lowers the number of malaria parasites in the blood, while lumefantrine stays in the body longer to help clear the remaining parasites. Taken as a tablet, Falsu LF 80 mg/480 mg Tablet is absorbed from the gut, and taking it with food helps the medicine work better.

Falsu LF 80 mg/480 mg Tablet is a higher-strength tablet, so it is generally suited for patients who need the specific artemether/lumefantrine dose prescribed by a doctor rather than a lower-strength tablet. Because it delivers a larger lumefantrine amount per tablet, it may be chosen when the prescribed regimen requires fewer tablets per dose, but the exact schedule still depends on the prescriber and the patient’s body weight.

• Treatment of uncomplicated malaria
• Plasmodium falciparum malaria, when susceptible
• Mixed malaria infections when prescribed
• Short-course antimalarial therapy under medical supervision

• Swallow the tablet with water as directed by your prescriber; do not crush or chew unless your clinician specifically tells you to.
• Take Falsu LF 80 mg/480 mg Tablet with food or milk to improve absorption, especially if you feel nauseated.
• Take doses at the exact times prescribed; antimalarial treatment works best when doses are not skipped or delayed.
• If you vomit soon after a dose, contact a clinician right away because you may need to repeat the dose.
• Do not use this tablet to self-treat a fever unless malaria has been diagnosed or strongly suspected by a healthcare professional.

Each Falsu LF 80 mg/480 mg Tablet provides 80 mg artemether plus 480 mg lumefantrine per tablet. This is a higher-strength tablet, and how often it is taken is determined by the doctor based on body weight, severity, and the prescribed artemether/lumefantrine schedule; antimalarial dosing is usually given over a short course, not as an ongoing daily medicine. There is no single max-per-day dose that fits every patient, so follow the exact prescribed regimen and do not take extra tablets.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Artemether + Lumefantrine may include:

• Headache
• Dizziness
• Nausea
• Vomiting
• Abdominal pain
• Loss of appetite
• Weakness or tiredness

• Do not use for severe malaria; severe malaria needs urgent hospital treatment.
• This higher-strength tablet should be used only under a clinician’s direction, because dosing is based on the patient’s weight and condition.
• Tell your doctor if you have a history of heart rhythm problems, low potassium or magnesium, or long QT syndrome.
• Avoid alcohol if it worsens dizziness, vomiting, or dehydration while you are ill.
• Tell your clinician about liver disease, because lumefantrine exposure may be increased.
• Use caution with driving or operating machinery if you feel dizzy, weak, or tired.
• Take special care if you are pregnant, breastfeeding, or if malaria symptoms persist after treatment.

• Other medicines that can affect heart rhythm, including certain antiarrhythmics and some antibiotics
• Strong CYP3A4 inducers such as rifampin, carbamazepine, or phenytoin, which may reduce effectiveness
• CYP3A4 inhibitors such as ketoconazole or some HIV medicines, which may increase exposure
• Other antimalarials unless specifically directed by a clinician
• Grapefruit products may affect lumefantrine levels and should be avoided unless your prescriber says otherwise

Store Falsu LF 80 mg/480 mg Tablet at room temperature in the original strip/box, away from moisture and direct heat.