Ranozine 500 mg Tablet SR

Ranozine 500 mg Tablet SR contains 500 mg of ranolazine in each prolonged-release tablet. It belongs to the antianginal medicine class and is used to help manage chronic angina, a type of chest pain caused by reduced blood flow to the heart. This medicine is not for sudden chest pain attacks; it is taken regularly to help reduce how often angina occurs and may improve exercise tolerance when prescribed appropriately.

How it works: Ranolazine helps the heart muscle use energy more efficiently by affecting the flow of sodium inside heart cells. In the Ranozine 500 mg Tablet SR form, this gradual-release tablet is taken by mouth to provide steady medicine levels that can help lower the frequency of angina episodes.

Ranozine 500 mg Tablet SR is a higher-strength ranolazine tablet that may be chosen for adults who need a stronger maintenance dose after a doctor has reviewed their symptoms, heart history, and other medicines. Because it is a sustained-release tablet, it is designed to release medicine gradually rather than all at once, so it should be swallowed whole and not split, crushed, or chewed. A doctor may use this 500 mg strength as part of a stepwise dosing plan, often before considering any increase.

• Chronic stable angina
• Prevention of angina symptoms
• Long-term chest pain control in adults
• Adjunct treatment when other heart medicines are not enough

• Swallow the Ranozine 500 mg Tablet SR whole with water; do not crush, split, or chew it.
• Take it exactly as prescribed, usually once or twice daily depending on your doctor's instructions.
• You may take it with or without food, but taking it the same way each time can help consistency.
• Take it at the same times every day to keep medicine levels steady.
• Do not use this tablet to stop a sudden chest pain attack; seek emergency care if chest pain is severe or different from usual.

Each Ranozine 500 mg Tablet SR provides 500 mg of ranolazine per tablet. This strength is commonly used as part of an adult maintenance schedule, and it may be taken once or twice daily depending on the prescriber’s plan; the maximum total is usually 2000 mg per day. Your doctor decides the dose based on your symptoms, kidney and liver function, and other medicines you take.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Ranolazine may include:

• Dizziness
• Headache
• Constipation
• Nausea
• Abdominal pain
• Weakness or fatigue
• Blurred vision

• Tell your doctor if you have liver disease, kidney problems, or a history of heart rhythm issues before taking Ranozine 500 mg Tablet SR.
• This medicine can prolong the QT interval in some people, so it may not be suitable if you already have certain rhythm disorders.
• Do not use it for sudden angina relief; keep emergency treatment for acute chest pain as directed by your doctor.
• Be careful when driving or using machinery until you know whether Ranozine 500 mg Tablet SR makes you dizzy.
• Avoid grapefruit or grapefruit juice unless your clinician says it is acceptable, because it can raise ranolazine levels.
• Alcohol may worsen dizziness or lightheadedness.
• Tell your prescriber about all prescription, OTC, and herbal products, especially heart medicines, antibiotics, and antifungals.

• Strong CYP3A inhibitors such as ketoconazole, clarithromycin, and some HIV medicines
• CYP3A inducers such as rifampin, carbamazepine, phenytoin, and St. John’s wort
• Other medicines that can prolong the QT interval
• Digoxin and some statins, which may need monitoring or dose adjustment

Store Ranozine 500 mg Tablet SR in the original strip/box at room temperature, away from moisture and excess heat, and keep it out of reach of children.