Fluo Cream

Fluo Cream is a topical cream containing fluorouracil, a prescription medicine in the antimetabolite class. Each tube is labelled as Fluo Cream with fluorouracil as the active ingredient, and the pack contains 10 tubes. It is used for skin conditions that a clinician has decided should be treated with fluorouracil cream, including actinic keratoses and some other abnormal or cancerous skin growths.

How it works: Fluorouracil works by blocking the growth of rapidly dividing cells, which helps destroy abnormal skin cells in the treated area. As a cream, it acts on the skin where it is applied, so the medicine concentrates its effect on the target spot rather than the whole body.

This is a topical cream strength that is meant to be applied directly to the affected skin, not taken by mouth. Because there are no other strengths or forms of Fluo Cream listed here, the doctor chooses this exact product when a cream is appropriate for the area being treated and the skin needs a formulation that spreads easily over the surface.

• Actinic keratosis
• Abnormal sun-damaged skin cells
• Superficial skin lesions
• Prescribed treatment for certain precancerous skin changes

• Apply Fluo Cream only to the skin exactly as prescribed by your doctor.
• Wash your hands before and after applying unless the hands are the area being treated.
• Use a thin layer and spread it gently over the prescribed area; do not use more than directed.
• Avoid getting the cream in your eyes, mouth, nose, or on broken skin unless your clinician told you to.
• Do not cover the treated area with bandages or tight dressings unless instructed.
• Use it at the times your doctor prescribed; this medicine is not taken with food or water.

Fluo Cream is a topical fluorouracil product, so the dose is measured by the amount applied to the skin, not by swallowing a tablet or capsule. The exact amount, how many times per day it is applied, and the total duration of treatment depend on the area being treated and your doctor’s instructions; there is no single universal daily maximum that fits every patient. Because this is a prescription-strength cream, your clinician decides the schedule and may adjust it based on how your skin responds.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Fluorouracil may include:

• Redness at the application site
• Burning or stinging sensation
• Dryness or peeling skin
• Itching or tenderness
• Crusting or soreness at the treated area
• Increased local irritation, which can be more noticeable as treatment continues

• Use only on skin and only on the area your doctor told you to treat.
• Do not apply to the eyes, lips, nostrils, inside the mouth, or genitals unless specifically directed.
• This medicine can make treated skin very sensitive; avoid sun exposure and use protection on uncovered skin.
• Tell your doctor if you have a history of severe reactions to fluorouracil or similar medicines.
• Use caution if you have reduced dihydropyrimidine dehydrogenase (DPD) activity, as serious toxicity can occur with fluorouracil.
• Do not use other irritating skin products, scrubs, or exfoliants on the treated area unless your clinician approves.
• If you are pregnant, trying to become pregnant, or breastfeeding, discuss risks and alternatives with your doctor before using this cream.

• Other topical acne or skin treatments that irritate the skin, such as retinoids or benzoyl peroxide
• Topical salicylic acid, alpha hydroxy acids, or exfoliating products
• Immunosuppressive medicines that may affect healing or skin response
• Warfarin, if the doctor believes systemic absorption could increase bleeding risk in some patients

Store Fluo Cream at room temperature, keep the tubes tightly closed, and protect them from excessive heat and freezing.