Cronodol 500 mg Tablet

Cronodol 500 mg Tablet is a prescription medicine that contains 500 mg of disulfiram in each tablet. It belongs to the alcohol deterrent medicines used to help support the treatment of alcohol use disorder. Cronodol 500 mg Tablet is taken only under medical supervision and is intended to help discourage drinking by making alcohol use unpleasant.

How it works: Disulfiram works by blocking the breakdown of alcohol in the body, so acetaldehyde can build up if alcohol is consumed. In tablet form, Cronodol 500 mg Tablet is swallowed and used to help create a strong aversive reaction to alcohol, which can support abstinence.

Cronodol 500 mg Tablet is a higher-strength disulfiram tablet, so it is typically used only when a doctor has decided that this strength is appropriate for the person’s treatment plan. Because there are no other strengths or forms listed for this brand, this 500 mg tablet represents the exact tablet strength being supplied rather than a lower-dose starter option.

• Alcohol use disorder support
• Alcohol deterrent therapy
• Relapse prevention when avoiding alcohol
• Part of a supervised treatment plan for abstinence

• Swallow Cronodol 500 mg Tablet whole with water unless your prescriber gives different directions.
• Take it exactly on the schedule your doctor prescribes; do not change the dose on your own.
• Do not take this tablet if you have recently used alcohol, including in drinks, medicines, mouthwash, or some cough syrups, unless your clinician has said it is safe.
• If your doctor tells you to start after stopping alcohol, follow the timing carefully because alcohol reactions can occur even after drinking has stopped.
• You can take it with or without food, but taking it with food may help reduce stomach upset.
• Do not crush or split the tablet unless your pharmacist or prescriber specifically tells you to do so.

Each Cronodol 500 mg Tablet provides 500 mg of disulfiram per tablet. The dosing schedule is individualized by the doctor; this strength may be taken once daily or on another schedule chosen for supervision, and the total daily amount should not be exceeded unless a clinician specifically instructs it.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Disulfiram may include:

• Drowsiness or fatigue, which may be more noticeable with the 500 mg tablet in some people
• Headache
• Metallic or garlic-like aftertaste
• Nausea or stomach upset
• Skin rash or itching
• Mild dizziness

• Do not drink alcohol while taking Cronodol 500 mg Tablet, and avoid alcohol for at least 12 hours before starting unless your doctor gives different instructions.
• Avoid alcohol hidden in medicines, mouthwash, sauces, tinctures, and some aftershave or hygiene products.
• This higher-strength tablet may cause stronger side effects, so it should be used only under close medical guidance.
• Tell your doctor if you have liver disease, kidney disease, diabetes, epilepsy, depression, or a history of heart disease or stroke.
• Do not use this medicine if you are taking or have recently taken metronidazole or other drugs your clinician says are incompatible with disulfiram.
• Use caution when driving or operating machinery until you know how this tablet affects you, especially if it causes dizziness or sleepiness.
• Tell every healthcare professional you see that you are taking disulfiram before any procedure or new prescription.

• Alcohol-containing products, including beverages and some medicines or personal care products
• Metronidazole
• Warfarin or other blood thinners, which may need closer monitoring
• Phenytoin or some other seizure medicines
• Isoniazid, which may increase the risk of nerve or liver problems

Store Cronodol 500 mg Tablet at room temperature in its original strip or box, away from moisture and heat, and keep it out of reach of children.