Medrol 16 mg Tablet

Medrol 16 mg Tablet contains 16 mg of methylprednisolone in each tablet. It is a corticosteroid, or steroid medicine, used to reduce inflammation and calm an overactive immune response. Medrol 16 mg Tablet may be prescribed for allergy-related flare-ups and other inflammatory conditions when a stronger tablet strength is needed. Because this is the highest Medrol tablet strength in our range, it is typically chosen when a doctor wants fewer tablets per dose.

How it works: Methylprednisolone in Medrol 16 mg Tablet works by blocking substances in the body that cause swelling, redness, itching, and irritation. As an oral tablet, it is swallowed and absorbed through the digestive tract to help reduce inflammation throughout the body.

Medrol 16 mg Tablet is the highest strength available in this brand range, above Medrol 4 mg Tablet and Medrol 8 mg Tablet. A doctor may choose Medrol 16 mg Tablet for people who need a larger methylprednisolone dose per tablet, which can make dosing simpler and reduce the number of tablets taken at once. It is not a starting strength for everyone, so the exact dose and taper schedule should be based on the prescriber’s plan.

• Allergic reactions
• Seasonal allergy flare-ups
• Inflammatory conditions
• Immune-related swelling
• Doctor-directed steroid taper

• Swallow the Medrol 16 mg Tablet whole with water unless your doctor gives different instructions.
• Take it exactly as prescribed; do not change the dose or stop suddenly on your own.
• Taking the tablet with food or milk can help reduce stomach upset.
• If you are prescribed a once-daily dose, morning dosing is often preferred to match the body’s natural steroid rhythm.
• If your doctor gives a taper, follow the taper schedule carefully even if you feel better.
• Do not crush or split the tablet unless your pharmacist or prescriber says it is okay.

Each Medrol 16 mg Tablet provides 16 mg of methylprednisolone per tablet, so it is a relatively high tablet strength compared with Medrol 4 mg and Medrol 8 mg. The exact number of tablets, how often to take them, and the maximum daily amount depend on the condition being treated and your doctor’s instructions; some regimens use higher total daily doses at first and then taper down.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Methylprednisolone may include:

• Increased appetite
• Stomach upset or indigestion
• Trouble sleeping
• Mood changes or feeling restless
• Headache
• Fluid retention or bloating
• Blood sugar increase, which may be more noticeable at this higher tablet strength

• Medrol 16 mg Tablet is a higher-strength steroid tablet, so use only as prescribed and do not self-adjust the dose.
• Longer or higher-dose use can raise blood sugar, blood pressure, and fluid retention risk.
• Tell your doctor if you have diabetes, high blood pressure, ulcers, glaucoma, osteoporosis, or liver disease.
• Avoid live vaccines unless your doctor says they are safe while you are taking methylprednisolone.
• Alcohol can irritate the stomach and may worsen stomach side effects.
• This medicine can make it harder for your body to fight infections, so report any signs of infection promptly.
• If you are taking it for an allergy flare, it treats inflammation but does not replace emergency treatment for severe breathing trouble or anaphylaxis.

• NSAIDs such as ibuprofen or naproxen, which can increase stomach irritation and bleeding risk
• Blood sugar medicines or insulin, because methylprednisolone can raise glucose levels
• Warfarin and other blood thinners, which may need closer monitoring
• Certain seizure medicines and rifampin, which can change steroid levels in the body
• Live vaccines, which may be less safe or less effective during steroid treatment

Store Medrol 16 mg Tablet at room temperature in the original strip or box, away from moisture, heat, and direct light.