Angispan TR 6.5 mg Tablet

Angispan TR 6.5 mg Tablet is a sustained-release nitroglycerin medicine used to help prevent angina pectoris, also called chest pain caused by reduced blood flow to the heart. Each tablet contains 6.5 mg of nitroglycerin, a nitrate anti-anginal drug that works over time rather than giving immediate relief. It is meant for people whose doctor has decided they need a longer-acting nitrate option to reduce angina episodes.

How it works: Nitroglycerin relaxes and widens blood vessels, which lowers the heart's workload and improves blood flow to the heart muscle. In the Angispan TR 6.5 mg Tablet form, the medicine is released slowly so its anti-anginal effect lasts longer.

Angispan TR 6.5 mg Tablet is a higher-strength sustained-release nitroglycerin product, so it is not the same as a fast-acting tablet for sudden chest pain. Doctors may choose this strength when a longer-acting nitrate effect is needed to help prevent angina through the day or night, depending on the person's symptoms and response to treatment. Because it is an extended-release form, it is taken differently from immediate-release nitroglycerin and should be used exactly as prescribed.

• Prevention of angina pectoris
• Reduction of chest pain episodes caused by heart ischemia
• Longer-acting nitrate therapy prescribed by a doctor
• Supportive treatment in chronic stable angina

• Swallow the Angispan TR 6.5 mg Tablet exactly as prescribed; do not crush, chew, or split it unless your prescriber specifically tells you to.
• Take it at the same time each day to maintain a steady effect from this sustained-release tablet.
• You may take it with or without food unless your doctor gives different instructions.
• Do not use this tablet as a quick rescue medicine for sudden chest pain; follow your doctor's plan for emergency angina relief.
• If a dose is missed, take it when remembered unless it is almost time for the next dose; do not double up.
• Stand up slowly after taking it because dizziness or lightheadedness can happen.

Each Angispan TR 6.5 mg Tablet provides 6.5 mg of nitroglycerin in a sustained-release form. The exact dosing schedule, how often it is taken, and the maximum daily amount depend on the doctor's prescription and the person's heart condition, because nitrate dosing must be individualized. This strength is intended for prescribed maintenance use, not self-adjusted dosing.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Nitroglycerin may include:

• Headache, which can be more noticeable with nitroglycerin and may happen more often when starting treatment
• Dizziness or lightheadedness
• Flushing or feeling warm
• Low blood pressure
• Fast heartbeat or palpitations
• Nausea
• Weakness or tired feeling

• Do not use if you take PDE-5 inhibitors for erectile dysfunction or pulmonary hypertension, because the combination can cause a dangerous drop in blood pressure.
• Use caution if you have low blood pressure, dehydration, anemia, or certain heart conditions, since this strength can further lower blood pressure.
• Avoid alcohol unless your doctor says it is safe, because alcohol can increase dizziness and fainting risk.
• Do not drive or use machinery until you know how Angispan TR 6.5 mg Tablet affects you.
• Tell your clinician if you have recent heart attack, severe headache history, or increased pressure inside the head, because nitroglycerin may not be appropriate in some situations.
• Do not stop or change the dose on your own, especially with a sustained-release nitrate tablet.
• If chest pain becomes more frequent, more severe, or different from usual, seek urgent medical advice.

• Sildenafil, tadalafil, and vardenafil
• Riociguat
• Other nitrates or nitrite medicines
• Alcohol
• Blood pressure medicines and certain heart medicines that can lower blood pressure further

Store Angispan TR 6.5 mg Tablet in its original container, tightly closed, at room temperature away from moisture, heat, and direct light.