Myovin Rectal Ointment

Myovin Rectal Ointment is a nitroglycerin ointment made by Cadila Pharmaceuticals, India, supplied in a strip/box of 10 bottles. Each bottle is labeled with the prescribed nitroglycerin amount on the pack, and this medicine belongs to the anti-anginal nitrate class. It is used to treat and help prevent chest pain related to angina pectoris, and the ointment form is chosen when a doctor wants nitroglycerin delivered through the skin or rectal area rather than as a tablet or spray.

How it works: Nitroglycerin relaxes and widens blood vessels, which lowers the heart’s workload and improves blood flow. In ointment form, it is absorbed slowly through the skin or rectal mucosa to provide a controlled nitrate effect.

Myovin Rectal Ointment is the ointment form of nitroglycerin, so it is meant for patients whose doctor has specifically chosen a topical/rectal nitrate preparation instead of an oral tablet or spray. The labeled bottle strength is used in small measured amounts, with the dose and schedule individualized because the medicine can lower blood pressure quickly and may cause headache or dizziness.

• Treatment of angina pectoris
• Prevention of chest pain episodes
• Relief of chest tightness related to heart ischemia
• Doctor-directed nitrate therapy when a topical/rectal form is preferred

• Use Myovin Rectal Ointment exactly as your doctor or pharmacist instructs; the amount is measured from the labeled bottle, not guessed.
• Apply only to the prescribed area and in the prescribed amount; do not use more often than directed.
• Wash hands before and after use, and avoid getting the ointment in the eyes, mouth, or broken skin unless your prescriber specifically told you to.
• If it is being used before activity that usually triggers angina, apply it at the time your doctor recommends; the onset can be slower than a fast-acting tablet or spray.
• Do not mix up the ointment with food-based instructions like chewing or swallowing, because this product is for topical/rectal use, not for oral use.
• If you miss a dose, use it only if your doctor’s schedule allows; do not double the amount to catch up.

Each bottle of Myovin Rectal Ointment contains the nitroglycerin strength shown on the label, and the exact amount per application depends on the prescription directions for that bottle. The medicine may be used on a set schedule or before expected angina triggers, but the frequency and maximum daily use must be determined by the doctor because nitroglycerin can cause low blood pressure and tolerance if overused.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Nitroglycerin may include:

• Headache, which is very common with nitroglycerin and may be more noticeable with this strength
• Dizziness or lightheadedness
• Flushing or feeling warm
• Low blood pressure
• Fast heartbeat or palpitations
• Mild nausea
• Application-site irritation or burning

• Use Myovin Rectal Ointment only if a clinician has assessed your heart condition and prescribed this nitroglycerin strength for you.
• Do not use with erectile dysfunction medicines such as sildenafil, tadalafil, or vardenafil because the combination can cause a dangerous blood pressure drop.
• Avoid alcohol, which can increase dizziness and low blood pressure with nitroglycerin.
• Use caution when driving or standing up quickly, especially after application, because this ointment can cause dizziness or fainting.
• Tell your doctor if you have severe anemia, recent head injury, increased intracranial pressure, or low blood pressure.
• Do not use other nitrate medicines at the same time unless your prescriber specifically tells you to.
• If chest pain is sudden, severe, or different from your usual angina, seek emergency care rather than trying to rely on repeated applications.

• PDE-5 inhibitors such as sildenafil, tadalafil, and vardenafil
• Riociguat
• Other nitrates such as isosorbide mononitrate or nitroglycerin products
• Alcohol
• Other blood pressure medicines, which may add to dizziness or hypotension

Store Myovin Rectal Ointment at room temperature in the original bottle, tightly closed, away from heat, moisture, and direct light.