Dabirex 75 mg Capsule

Dabirex 75 mg Capsule contains 75 mg of dabigatran etexilate in each capsule. It is an oral anticoagulant, or blood thinner, used to help prevent and treat certain dangerous blood clots and to lower the risk of stroke in people with non-valvular atrial fibrillation. Dabirex 75 mg Capsule is a prescription medicine and should be used only when a clinician has determined it is appropriate for your situation.

How it works: Dabigatran etexilate is a prodrug that the body converts into dabigatran, which blocks thrombin, a key enzyme needed to form blood clots. By reducing thrombin activity, Dabirex 75 mg Capsule helps the blood clot less easily.

Dabirex 75 mg Capsule is a lower-strength dabigatran capsule that may be chosen for people who need dose adjustment because of kidney function, age, drug interactions, or bleeding risk. Compared with higher dabigatran strengths, the 75 mg capsule lets a doctor tailor therapy more carefully, rather than using a one-size-fits-all dose.

• Reduce stroke risk in non-valvular atrial fibrillation
• Treat blood clots in the veins
• Help prevent deep vein thrombosis
• Help prevent pulmonary embolism
• Reduce the chance of clot recurrence after treatment

• Swallow the Dabirex 75 mg Capsule whole with a full glass of water; do not open, crush, or chew the capsule.
• Take it exactly as prescribed, at the same time each day if you are told to take it once daily, or about 12 hours apart if prescribed twice daily.
• You may take Dabirex 75 mg Capsule with or without food, but taking it with food may help if it upsets your stomach.
• Keep the capsule in its original strip/box until you are ready to take it, because moisture can affect the medicine.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double up unless your prescriber tells you to.
• Do not stop Dabirex 75 mg Capsule suddenly without medical advice, because stopping can raise your risk of a serious clot.

Each Dabirex 75 mg Capsule provides 75 mg of dabigatran etexilate per capsule. The dosing schedule can vary by reason for use and by kidney function, and a doctor may prescribe it once or twice daily; the total daily amount is decided by the prescriber and should not be changed on your own. This is a lower-strength capsule, so it is not a standard over-the-counter dose and should be taken only as directed.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Dabigatran Etexilate may include:

• Bruising more easily
• Bleeding from the nose or gums
• Upset stomach
• Heartburn or indigestion
• Nausea
• Mild stomach pain

• Do not use Dabirex 75 mg Capsule if you have active bleeding or a known allergy to dabigatran etexilate.
• Tell your doctor if you have kidney problems, because this lower strength may be chosen when kidney function is reduced.
• Use extra caution if you are older or have a history of bleeding, ulcers, or falls.
• Avoid taking other blood thinners, aspirin, or NSAIDs unless your doctor specifically says it is safe.
• Limit alcohol, since it can increase bleeding risk and stomach irritation.
• Tell every clinician, dentist, and surgeon that you take Dabirex 75 mg Capsule before any procedure.
• Do not drive or operate machinery if you feel dizzy, weak, or unwell from bleeding or other side effects.

• Other anticoagulants such as warfarin, heparin, apixaban, rivaroxaban, or edoxaban
• Antiplatelet medicines such as aspirin, clopidogrel, or ticagrelor
• NSAIDs such as ibuprofen, naproxen, or diclofenac
• P-glycoprotein inhibitors or inducers that can change dabigatran levels
• Certain heart medicines and antibiotics that may raise bleeding risk or alter how the capsule works

Store Dabirex 75 mg Capsule in the original strip/box, tightly protected from moisture, and keep it at room temperature away from heat and out of reach of children.