Pradaxa 75 mg Capsule

Pradaxa 75 mg Capsule is a prescription anticoagulant that contains 75 mg of dabigatran etexilate in each capsule. It belongs to the blood thinner class and is used to help prevent harmful blood clots and reduce the risk of stroke in certain patients, including people with atrial fibrillation and patients being treated for or preventing clots as directed by a doctor. Pradaxa 75 mg Capsule works differently from many older blood thinners, so the dose is chosen carefully based on kidney function and bleeding risk. It is supplied as a capsule from Boehringer Ingelheim Pharmaceuticals in a strip/box of 10 capsules.

How it works: Dabigatran etexilate is a prodrug that changes in the body into dabigatran, which blocks thrombin, a key protein needed to form blood clots. In capsule form, Pradaxa 75 mg helps thin the blood by making it harder for clots to develop or grow.

Pradaxa 75 mg Capsule is a lower-strength option compared with Pradaxa 110 mg Capsule and Pradaxa 150 mg Capsule, so it may be selected for patients who need a more cautious dose because of kidney problems, age, drug interactions, or a higher bleeding risk. It is not a starter dose for everyone, and it should only be used when a clinician has specifically assessed that this 75 mg capsule is the right fit.

• Reduce stroke risk in nonvalvular atrial fibrillation
• Treat deep vein thrombosis (DVT)
• Treat pulmonary embolism (PE)
• Help prevent DVT/PE from coming back

• Swallow the Pradaxa 75 mg Capsule whole with a full glass of water; do not open, crush, or chew it.
• Take it exactly as prescribed, usually twice daily for many approved uses, but follow your doctor’s instructions for this 75 mg strength.
• You may take it with or without food.
• Keep the capsules in the original container or blister pack until ready to use, because moisture can affect the medicine.
• Do not stop Pradaxa 75 mg Capsule suddenly unless your doctor tells you to, because stopping can raise the risk of clotting.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double up.

Each Pradaxa 75 mg Capsule provides 75 mg of dabigatran etexilate. This strength may be taken once or twice daily depending on the condition being treated and the prescriber’s plan, and the maximum daily amount depends on the approved indication and the patient’s kidney function. Your doctor decides the exact dose schedule for Pradaxa 75 mg Capsule; this is a prescription blood thinner that is not meant for self-adjusting.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Dabigatran Etexilate may include:

• Bruising more easily
• Bleeding longer after cuts
• Indigestion or stomach pain
• Heartburn or acid reflux
• Nausea
• Diarrhea

• Pradaxa 75 mg Capsule can increase the risk of bleeding, so tell your doctor about any recent surgery, injury, or planned procedure.
• This lower-strength capsule is often chosen for patients who need extra caution because of reduced kidney function or interacting medicines.
• Avoid over-the-counter NSAIDs like ibuprofen or naproxen unless your doctor says they are safe, because they can raise bleeding risk.
• Limit alcohol, since heavy drinking can increase the chance of stomach irritation and bleeding.
• Tell your doctor if you have a history of stomach ulcers, bleeding disorders, liver disease, or heart valve problems.
• Do not use this medicine to stop a clot on your own or to replace regular follow-up labs and checkups, especially if your dose is based on kidney function.
• Be careful with activities that could cause injury or falls because bleeding may be harder to stop.

• Other blood thinners such as warfarin, apixaban, rivaroxaban, heparin, or clopidogrel
• NSAIDs such as ibuprofen, naproxen, or high-dose aspirin
• Strong P-gp inhibitors such as dronedarone, ketoconazole, or verapamil, which can raise dabigatran levels
• Rifampin, which can lower dabigatran levels and reduce effectiveness
• Herbal supplements that may affect bleeding, such as ginkgo, garlic, or St. John’s wort

Store Pradaxa 75 mg Capsule in the original container at room temperature and keep it dry, away from moisture and heat.