Pentanerv 450 mg Tablet SR

Pentanerv 450 mg Tablet SR is a prescription medicine that contains gabapentin 450 mg in each sustained-release tablet. It belongs to the anti-convulsant class and is used to help control certain types of seizures and to treat nerve pain in some patients. Because it is a higher-strength tablet, Pentanerv 450 mg Tablet SR is generally used when a doctor has already decided that this specific dose is appropriate for the patient.

How it works: Gabapentin calms overactive nerve signals in the brain and nerves, which can help reduce seizure activity and nerve pain. In tablet form, Pentanerv 450 mg Tablet SR is designed to release the medicine gradually so the effect is spread out over time.

Pentanerv 450 mg Tablet SR is a higher-strength gabapentin tablet, so it is not usually a starting dose for everyone. A doctor may choose this strength for patients who need a larger individual dose, want fewer tablets per dose, or are already stabilized on gabapentin and need a maintenance strength that fits their treatment plan.

• Adjunct treatment of partial-onset seizures
• Nerve pain from damaged nerves
• Neuropathic pain symptoms
• Long-term maintenance therapy when prescribed by a clinician

• Swallow Pentanerv 450 mg Tablet SR whole with water; do not crush, split, or chew it unless your doctor or pharmacist specifically says it is safe to do so.
• Take it exactly at the times prescribed, because sustained-release tablets are meant to give a steady effect over time.
• It can be taken with or without food, but taking it the same way each day may help you remember your doses.
• Do not take an extra tablet to make up for a missed dose unless your prescriber tells you to do so.
• Avoid alcohol and be careful with activities that need alertness, especially when you first start Pentanerv 450 mg Tablet SR or after a dose increase.

Each Pentanerv 450 mg Tablet SR provides 450 mg of gabapentin in one sustained-release tablet. How often it is taken can vary by the condition being treated and the patient's other medicines; some patients may take it once daily or more than once daily as directed, and the doctor sets the exact schedule and maximum daily amount. Do not adjust the dose on your own, because the 450 mg strength is chosen to fit a specific treatment plan.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Gabapentin may include:

• Drowsiness
• Dizziness
• Sleepiness
• Unsteady walking or poor coordination
• Fatigue
• Swelling in the hands or feet
• Nausea

• Pentanerv 450 mg Tablet SR is a higher-strength gabapentin tablet, so use only if your doctor has specifically prescribed this dose.
• Do not drive, use machinery, or do anything that needs full alertness until you know how Pentanerv 450 mg Tablet SR affects you.
• Avoid alcohol because it can increase sleepiness and dizziness.
• Tell your doctor if you have kidney disease, since gabapentin dosing may need adjustment.
• Use extra caution if you take opioid pain medicines, sleeping pills, or anxiety medicines because sedation can be stronger.
• Do not stop taking Pentanerv 450 mg Tablet SR suddenly without medical advice, especially if you use it for seizures.
• If you notice swelling, mood changes, or a worsening of seizures or pain, contact your prescriber promptly.

• Opioid pain medicines such as morphine, oxycodone, or hydrocodone
• Alcohol
• Sedatives or sleeping medicines
• Benzodiazepines such as alprazolam or lorazepam
• Antacids containing aluminum or magnesium, which can affect gabapentin absorption

Store Pentanerv 450 mg Tablet SR in its original strip/box at room temperature, away from moisture, heat, and direct light.