Graniset 1 mg Tablet

Graniset 1 mg Tablet is a prescription anti-emetic that contains 1 mg of granisetron in each tablet. It belongs to the 5-HT3 receptor antagonist class and is used to help prevent or treat nausea and vomiting, especially when these symptoms are triggered by cancer treatment or surgery. This strength is an oral tablet made by Sun Pharmaceutical Industries Ltd. and comes in a strip/box of 4 tablets.

How it works: Granisetron blocks serotonin signals at 5-HT3 receptors in the gut and the brain that can trigger nausea and vomiting. As a tablet, Graniset 1 mg Tablet is swallowed and absorbed through the digestive tract to provide antiemetic effect.

Graniset 1 mg Tablet is a full-strength oral granisetron tablet, so it is typically used only when a clinician has decided this dose is appropriate for the patient’s age, condition, and treatment plan. Because there are no other Graniset strengths/forms listed here, this 1 mg tablet should be viewed as the exact product prescribed for a specific anti-nausea schedule rather than as a starter or lower-dose version.

• Prevention of chemotherapy-induced nausea and vomiting
• Prevention of radiation-induced nausea and vomiting
• Prevention of postoperative nausea and vomiting
• Treatment of nausea and vomiting when prescribed by a doctor

• Swallow Graniset 1 mg Tablet whole with a glass of water unless your doctor gives different instructions.
• Take it exactly at the time your doctor prescribes; for nausea prevention this is often before the trigger event such as chemotherapy, radiation, or surgery.
• Do not crush, chew, or split the tablet unless a pharmacist or prescriber tells you it is safe to do so.
• You may take it with or without food if your doctor does not advise otherwise.
• If you vomit soon after taking a dose, do not take an extra tablet unless your doctor tells you to.
• Use the exact dose schedule your clinician provides, since anti-nausea medicines are often timed carefully.

Each Graniset 1 mg Tablet provides 1 mg of granisetron per tablet. Depending on the reason it is prescribed, it may be taken once or repeated on a schedule set by the doctor, but the exact dose and maximum daily amount must be determined by the prescriber for your situation. Do not take more tablets than instructed, even if nausea returns.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Granisetron may include:

• Headache
• Constipation
• Dizziness
• Weakness or fatigue
• Diarrhea
• Abdominal discomfort
• Sleepiness in some people

• Use caution if you have a history of heart rhythm problems or long QT syndrome.
• Tell your doctor about all medicines you take, especially other drugs that can affect serotonin or heart rhythm.
• Do not drive or use machinery if the tablet makes you dizzy or sleepy.
• Let your clinician know if you have severe constipation, bowel blockage, or trouble passing stool.
• Use extra caution if you are pregnant or breastfeeding and ask your doctor whether this tablet is appropriate.
• Follow the prescribed timing closely; antiemetic benefit depends on taking Graniset 1 mg Tablet as directed.
• Seek medical advice before use if you have liver disease or significant dehydration from vomiting.

• Other serotonin-affecting medicines such as SSRIs, SNRIs, MAO inhibitors, tramadol, or linezolid
• Other drugs that can prolong the QT interval, including some antiarrhythmics and certain antibiotics
• Apomorphine
• Alcohol, which may worsen dizziness or drowsiness

Store Graniset 1 mg Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light.