Instaset Syrup

Instaset Syrup is an ondansetron oral anti-emetic syrup made by Votary Laboratories (India) Ltd. Each bottle contains ondansetron in the labeled strength, and the product is packed in a strip/box of 10 bottles. It belongs to the 5-HT3 receptor antagonist class and is used to help prevent and treat nausea and vomiting from causes such as illness, medicines, surgery, or chemotherapy when a doctor prescribes it.

How it works: Ondansetron in Instaset Syrup blocks serotonin signals in the gut and the brain that can trigger nausea and vomiting. As a syrup, it is taken by mouth and is absorbed to start working after it is swallowed.

Instaset Syrup is a liquid ondansetron option, which can be easier to swallow and easier to adjust than tablets for people who need an oral anti-nausea medicine. Because it is an as-labelled syrup and not a lower-strength tablet or injection, a doctor chooses it when a liquid form is preferred for dosing flexibility, swallowing difficulty, or a need for oral administration.

• Prevention of nausea and vomiting
• Treatment of nausea and vomiting
• Nausea from chemotherapy
• Nausea after surgery
• Medicine-related nausea

• Shake the bottle well before each dose if directed on the label or by your pharmacist.
• Measure Instaset Syrup with an accurate oral syringe or dosing cup, not a kitchen spoon.
• Take it exactly as prescribed, with or without food.
• If it is used for a known trigger such as chemotherapy or surgery, take it at the timing your doctor gives you.
• Do not double up doses if you miss one unless your prescriber tells you to do so.
• Swallow the syrup by mouth only; do not inject it or mix it with other medicines unless instructed.

The dose supplied by Instaset Syrup is the ondansetron amount listed on the bottle label, and the exact number of milligrams per dose depends on that labeled strength. It may be taken once or repeated during the day only as prescribed, but the total daily amount must stay within the limit set by the prescriber for your specific condition and age. Your doctor decides the right schedule for this strength based on why it is being used and your other medicines.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Ondansetron may include:

• Headache
• Constipation
• Diarrhea
• Dizziness
• Fatigue
• Mild stomach discomfort
• Less commonly, dose-related drowsiness or lightheadedness

• Use Instaset Syrup only as directed by a doctor, especially if you have heart rhythm problems.
• Tell your doctor if you have a history of long QT syndrome or low potassium or magnesium.
• Use caution if you are taking other medicines that can affect heart rhythm.
• Avoid alcohol if it makes dizziness or sleepiness worse.
• Do not drive or operate machinery if the syrup makes you dizzy or tired.
• Tell your doctor about liver disease, since ondansetron dosing may need adjustment.
• If you are pregnant or breastfeeding, ask a clinician before using this medicine.

• Other serotonin-raising medicines such as SSRIs, SNRIs, MAOIs, or certain migraine medicines
• Medicines that can prolong the QT interval, including some antiarrhythmics and antibiotics
• Apomorphine
• Rifampin or other strong enzyme inducers that may reduce ondansetron exposure
• Phenytoin or carbamazepine, which can lower ondansetron levels

Store Instaset Syrup at room temperature in the original bottle, tightly closed, and protect it from excess heat, light, and moisture.