Comantrel 100 Capsule

Comantrel 100 Capsule is an oral capsule containing amantadine 100 mg in each capsule. It belongs to the anti-parkinsonian medicine class and is used to help manage symptoms of Parkinson’s disease and certain drug-induced movement problems, such as stiffness, tremor, and slowness of movement. Because it is a 100 mg capsule, Comantrel 100 Capsule is a prescription-strength option that a clinician may select when a patient needs this standard amantadine dose in a convenient capsule form. It should be used only under medical supervision, since amantadine dosing depends on the condition being treated and the patient’s overall health.

How it works: Amantadine helps reduce Parkinsonian symptoms by increasing the action of dopamine in the brain, which can improve movement and reduce stiffness and tremor. In capsule form, Comantrel 100 Capsule delivers this medicine by mouth so it is absorbed into the bloodstream and starts working according to the dosing schedule your doctor sets.

Comantrel 100 Capsule provides amantadine 100 mg per capsule, which is a common adult capsule strength for this medicine. Since there are no other listed strengths or forms of this brand, this product fits the typical oral dosing pattern for amantadine and may be chosen for patients who can take capsules and need a standard dose that can be adjusted by the prescriber. A doctor may choose Comantrel 100 Capsule because it is easy to swallow and allows dosing to be spaced through the day when needed.

• Parkinson’s disease symptom relief
• Tremor and stiffness management
• Slowness of movement (bradykinesia)
• Drug-induced movement symptoms
• Adjunct treatment when a clinician prescribes amantadine

• Swallow Comantrel 100 Capsule whole with water; do not crush, chew, or open it unless your pharmacist or doctor tells you to.
• Take it exactly at the times prescribed, since spacing the doses can help maintain a steady effect.
• If it upsets your stomach, it may be taken with food or milk unless your prescriber says otherwise.
• Try to take the last dose earlier in the day if advised, because amantadine can sometimes cause trouble sleeping.
• Do not take extra capsules to make up for a missed dose unless your doctor or pharmacist instructs you to do so.

Each Comantrel 100 Capsule contains amantadine 100 mg. The number of times per day you take it depends on the reason it was prescribed, your age, kidney function, and how you respond to treatment; your doctor decides the exact schedule. Because this is a 100 mg capsule, the daily maximum is not the same for everyone and should only be set by a prescriber.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Amantadine may include:

• nausea
• dizziness
• dry mouth
• constipation
• insomnia or trouble sleeping
• lightheadedness
• blurred vision

• Use caution if you have kidney disease, because amantadine may build up in the body and side effects can be more likely with Comantrel 100 Capsule.
• This medicine can cause dizziness or blurred vision, so be careful driving or operating machinery until you know how it affects you.
• Alcohol may worsen dizziness, sleepiness, or confusion.
• Tell your doctor if you have a history of seizures, heart disease, glaucoma, or mental health conditions.
• Older adults may be more sensitive to confusion, hallucinations, and falls.
• Do not stop taking amantadine suddenly without medical advice, especially if you have Parkinson’s disease.
• Tell your clinician about all medicines you take, because some can increase side effects or affect heart rhythm.

• other medicines that affect the brain, such as sedatives or anticholinergic drugs
• alcohol
• certain blood pressure medicines that can increase dizziness or fainting risk
• medicines that may affect kidney function or amantadine removal
• other Parkinson’s medicines unless your doctor says they can be combined

Store Comantrel 100 Capsule in its original strip or box at room temperature, away from moisture, heat, and direct light.