Prexol 0.50 Tablet

Prexol 0.50 Tablet is a prescription medicine that contains pramipexole 0.50 mg in each tablet. It belongs to the anti-Parkinsonian drug class, specifically a dopamine agonist. Doctors use Prexol 0.50 Tablet to help treat Parkinson’s disease symptoms such as tremor, stiffness, and slowness of movement. It is a tablet taken by mouth and should be used only as directed by a clinician.

How it works: Pramipexole works by stimulating dopamine receptors in the brain, helping replace some of the signal that is reduced in Parkinson’s disease. As a tablet, Prexol 0.50 Tablet is absorbed after swallowing and helps improve movement symptoms over time when taken regularly.

Prexol 0.50 Tablet is a higher tablet strength, so it is usually chosen after a doctor has assessed that a lower dose is not enough or that the patient is being moved up in treatment. Compared with lower-strength pramipexole tablets, this 0.50 mg tablet gives a larger dose in each tablet and may be more likely to cause drowsiness, dizziness, or low blood pressure if it is increased too quickly. It is not meant for self-adjusting dose changes.

• Parkinson’s disease
• Tremor reduction
• Stiffness and rigidity relief
• Slowness of movement (bradykinesia)
• Motor symptom control as part of a treatment plan

• Swallow Prexol 0.50 Tablet whole with water unless your doctor gives different instructions.
• Take it at the same time each day to help you remember doses.
• It may be taken with or without food; taking it with food can help if it upsets your stomach.
• Do not crush, split, or chew the tablet unless your prescriber or pharmacist says it is safe to do so.
• If it makes you sleepy or dizzy, be careful when standing up quickly and avoid driving until you know how it affects you.
• Do not increase or stop Prexol 0.50 Tablet on your own; dose changes should be gradual and supervised.

Each Prexol 0.50 Tablet contains pramipexole 0.50 mg. This strength may be taken once daily or divided into several doses per day depending on the treatment plan, but the exact schedule is individualized by the doctor. The maximum daily dose depends on the reason it is prescribed and the patient’s kidney function, so your prescriber should set the dose and any increases.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Pramipexole may include:

• Nausea
• Dizziness
• Sleepiness or fatigue
• Constipation
• Dry mouth
• Swelling in the legs or feet
• Low blood pressure when standing up, which may be more noticeable at this higher strength

• Prexol 0.50 Tablet can cause drowsiness, so use caution with driving, machinery, or anything that requires alertness.
• Stand up slowly because this strength may cause orthostatic low blood pressure and lightheadedness.
• Tell your doctor if you have kidney disease, since pramipexole dosing may need adjustment.
• Use caution if you drink alcohol, because it can worsen sleepiness and dizziness.
• Report hallucinations, confusion, or mood and behavior changes promptly, especially in older adults.
• Do not stop Prexol 0.50 Tablet suddenly unless your doctor tells you to do so.
• Tell your prescriber about heart disease or swelling, since leg swelling can occur with pramipexole.

• Other medicines that cause sleepiness, including opioids, benzodiazepines, and some sleep aids
• Alcohol
• Antipsychotic medicines, which can reduce the effect of pramipexole
• Cimetidine, which can raise pramipexole levels
• Medications that lower blood pressure, which can increase dizziness and fainting

Store Prexol 0.50 Tablet at room temperature in its original strip/box, away from moisture, heat, and out of reach of children.