Syndopa 25 + 250 mg Tablet

Syndopa 25 + 250 mg Tablet is a prescription anti-Parkinsonian medicine that contains carbidopa 25 mg and levodopa 250 mg in each tablet. It is used to help manage symptoms of Parkinson’s disease and Parkinson-like movement problems such as tremor, stiffness, slowness, and trouble with balance. This combination helps improve movement by increasing dopamine activity in the brain. Syndopa 25 + 250 mg Tablet is a higher-strength tablet and is usually chosen when a doctor wants a stronger levodopa dose in a convenient single tablet.

How it works: Carbidopa helps levodopa reach the brain by reducing how much levodopa is broken down before it gets there, which means more medicine can work where it is needed. The tablet then helps replace low dopamine in the brain, which can improve movement and reduce Parkinson’s symptoms.

Syndopa 25 + 250 mg Tablet is the higher-strength tablet in this carbidopa/levodopa combination, so it may be selected for people who need more levodopa per dose than lower-strength tablets can provide. It can be useful when symptoms are not well controlled on smaller strengths, but it is not meant to be started casually or self-adjusted because the 250 mg levodopa strength can cause stronger side effects if the dose is too high.

• Parkinson’s disease symptom control
• Tremor and shaking
• Muscle stiffness and rigidity
• Slowness of movement (bradykinesia)
• Difficulty with walking and balance
• Parkinson-like symptoms from other causes, when prescribed

• Swallow the Syndopa 25 + 250 mg Tablet whole with water unless your doctor tells you otherwise.
• Take it at the same times each day to help keep symptoms more steady.
• If it upsets your stomach, your doctor may advise taking it with a small snack; a high-protein meal can reduce absorption.
• Do not crush or split the tablet unless a pharmacist or doctor specifically says the tablet can be altered.
• Stand up slowly after taking it, especially when you are first starting or changing dose, because it can lower blood pressure.
• If your doctor instructs you to take doses at set times, follow that schedule closely; do not take extra tablets for sudden symptom flare-ups.

Each Syndopa 25 + 250 mg Tablet provides carbidopa 25 mg plus levodopa 250 mg, which is a substantial levodopa dose in one tablet. Some people take it multiple times a day, but the exact schedule and maximum daily amount are individualized by the prescriber based on symptoms, response, and side effects. Do not increase the number of tablets or change timing on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Carbidopa + Levodopa may include:

• Nausea or vomiting
• Dizziness or lightheadedness
• Sleepiness
• Low blood pressure when standing
• Dry mouth
• Diarrhea or constipation
• Involuntary movements (more likely as the levodopa dose rises)

• Syndopa 25 + 250 mg Tablet is a higher-strength carbidopa/levodopa tablet, so dose changes should be supervised by a doctor.
• It can cause drowsiness or sudden sleep episodes, so avoid driving or operating machinery until you know how it affects you.
• Alcohol can worsen dizziness and drowsiness.
• Use caution if you have heart disease, arrhythmia, glaucoma, liver disease, kidney disease, or a history of ulcers.
• Do not stop the medicine suddenly unless your prescriber tells you to do so.
• Tell your doctor if you have a history of hallucinations, impulse-control problems, or severe mood changes.
• Protein-rich meals may delay or reduce the effect of this tablet, so meal timing may matter.

• Nonselective MAO inhibitors can cause a dangerous reaction with carbidopa/levodopa.
• Certain antipsychotics and anti-nausea drugs that block dopamine can reduce its effect.
• Iron supplements may reduce absorption of levodopa.
• Blood pressure medicines may increase dizziness or low blood pressure.
• Other Parkinson’s medicines may require dose adjustment when used together.

Store Syndopa 25 + 250 mg Tablet in its original strip at room temperature, away from excess heat, moisture, and direct light.