Syndopa Plus 25 + 100 mg Tablet

Syndopa Plus 25 + 100 mg Tablet is a prescription anti-Parkinsonian medicine that contains carbidopa 25 mg and levodopa 100 mg in each tablet. It belongs to the dopaminergic therapy class and is used to help manage Parkinson’s disease and Parkinsonian symptoms such as tremor, stiffness, and slowed movement. This 100 mg levodopa tablet is one of the stronger immediate-release combinations and is meant for patients whose doctor has already assessed their dose needs. By improving dopamine levels in the brain, Syndopa Plus 25 + 100 mg Tablet can help movement become smoother and easier.

How it works: Carbidopa helps prevent levodopa from breaking down too early outside the brain, so more levodopa can reach the brain where it is needed. In this tablet form, levodopa is converted to dopamine in the brain, which helps reduce Parkinson’s symptoms like tremor, stiffness, and slowness.

Each Syndopa Plus 25 + 100 mg Tablet provides 100 mg of levodopa, so it is not a low-dose starter tablet for everyone. It may suit people who need a larger levodopa dose per tablet for symptom control, while still keeping carbidopa in the combination to help reduce nausea and improve levodopa delivery to the brain. A doctor may choose this strength to fit an individualized schedule and to reduce the number of tablets needed compared with lower-strength options.

• Parkinson’s disease
• Parkinsonian symptoms
• Tremor control
• Muscle stiffness
• Slowness of movement

• Take Syndopa Plus 25 + 100 mg Tablet by mouth with a glass of water, exactly as prescribed.
• Take it at the same times each day to keep symptoms more stable.
• If it upsets your stomach, your doctor may advise taking it with a small snack; high-protein meals can reduce absorption.
• Do not crush, chew, or split the tablet unless your doctor or pharmacist tells you it is okay.
• Avoid taking it with a very large meal right when symptoms are being controlled, because food can delay or reduce the effect.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.

Syndopa Plus 25 + 100 mg Tablet provides 100 mg of levodopa per tablet with 25 mg of carbidopa. The exact dose and how often you take it depend on your doctor’s plan, your symptoms, and how you respond; some patients take it several times a day, but the schedule must be individualized. Do not exceed the maximum daily amount your prescriber sets, because too much levodopa can increase side effects and dosing needs are different for each person.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Carbidopa + Levodopa may include:

• nausea
• vomiting
• dizziness
• sleepiness
• loss of appetite
• dry mouth
• lightheadedness when standing

• This 100 mg tablet is a higher levodopa strength, so it should be used only under a doctor’s supervision after dose assessment.
• It can cause dizziness or sleepiness, so be careful when driving or using machinery until you know how it affects you.
• Alcohol may worsen dizziness, drowsiness, and low blood pressure.
• Tell your doctor if you have heart disease, arrhythmias, glaucoma, liver disease, kidney disease, or a history of ulcers.
• This medicine may lower blood pressure when standing, especially when treatment starts or the dose changes.
• Do not stop Syndopa Plus 25 + 100 mg Tablet suddenly unless your prescriber tells you to, because symptoms can worsen.
• Tell your doctor about mood changes, depression, or unusual urges, as dopaminergic medicines can affect behavior.

• MAO inhibitors or recent MAOI use
• iron supplements or multivitamins with iron
• protein-heavy meals that can reduce levodopa absorption
• certain antipsychotics that block dopamine
• blood pressure medicines that may increase dizziness

Store Syndopa Plus 25 + 100 mg Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light, and keep it out of reach of children.