Metrogyl 400 mg Tablet

Metrogyl 400 mg Tablet is an antibiotic tablet that contains 400 mg of metronidazole in each tablet. It belongs to the nitroimidazole class and is used to treat certain bacterial and protozoal infections, including infections in the gut, reproductive tract, teeth, skin, and other body sites when prescribed. Metrogyl 400 mg Tablet is taken by mouth and should be used only for infections your clinician has diagnosed.

How it works: Metronidazole works by entering susceptible bacteria and protozoa and damaging their DNA, which stops them from growing and surviving. As a tablet, Metrogyl 400 mg Tablet delivers the medicine systemically after swallowing, helping treat infections throughout the body where metronidazole is indicated.

Metrogyl 400 mg Tablet is the higher-strength option compared with Metrogyl 200 mg Tablet, so it can be more suitable when a doctor wants each dose to provide more metronidazole. Because each tablet contains 400 mg, it may reduce the number of tablets needed per dose, but it is not meant to be chosen on your own. Your prescriber will decide whether this strength is appropriate based on the infection being treated, your age, and your medical history.

• Bacterial vaginosis
• Trichomoniasis
• Amoebiasis
• Giardiasis
• Dental and gum infections
• Certain abdominal or pelvic infections

• Swallow Metrogyl 400 mg Tablet whole with water unless your doctor gives different instructions.
• Take it exactly as prescribed and at evenly spaced times to keep the medicine level steady.
• It can be taken with or after food to help reduce stomach upset.
• Do not drink alcohol during treatment and for at least 3 days after your last dose.
• Finish the full course even if you start feeling better.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.

Each Metrogyl 400 mg Tablet provides 400 mg of metronidazole per tablet, so the total daily amount depends on how many tablets your doctor prescribes. Depending on the infection, it may be taken once, twice, or three times daily, and the maximum daily dose is set by the prescriber based on the condition being treated. Do not adjust the number of Metrogyl 400 mg Tablets on your own, because the right dose varies by infection and patient factors.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Metronidazole may include:

• Nausea
• Metallic or bitter taste
• Loss of appetite
• Diarrhea or stomach cramps
• Headache
• Dizziness
• Dark urine

• Do not drink alcohol while taking Metrogyl 400 mg Tablet or for at least 3 days after finishing it, because a severe reaction can occur.
• Use caution if you have liver disease, since metronidazole may stay in the body longer.
• Tell your doctor if you have a history of blood disorders, seizures, or nervous system problems.
• This higher-strength tablet should be used only when the prescribed dose matches the 400 mg strength; do not split or combine doses unless instructed.
• Metronidazole can cause dizziness or drowsiness, so be careful driving or operating machinery until you know how it affects you.
• Tell your clinician about all medicines you take, including blood thinners and seizure medicines, because interactions can be important.
• If you develop numbness, severe stomach pain, or an allergic rash, seek medical advice promptly.

• Alcohol and alcohol-containing medicines or products
• Warfarin and other blood thinners
• Lithium
• Phenytoin or phenobarbital
• Disulfiram

Store Metrogyl 400 mg Tablet at room temperature in its original strip or box, away from moisture, heat, and direct light.