AF 300 Tablet

AF 300 Tablet is an oral antifungal medicine that contains fluconazole 300 mg in each tablet. It belongs to the triazole class of antifungals and is used to treat certain fungal and yeast infections, including infections caused by Candida and other susceptible fungi. AF 300 Tablet is taken by mouth and works throughout the body, so it may be chosen when a clinician wants a higher single-tablet fluconazole strength rather than a lower-dose tablet. This exact strength should be used only when prescribed for your specific infection and treatment plan.

How it works: Fluconazole in AF 300 Tablet works by blocking a fungal enzyme the organism needs to make ergosterol, an important part of its cell membrane. Without that membrane support, the fungus cannot grow well and may die off or spread more slowly.

AF 300 Tablet provides 300 mg of fluconazole per tablet, which is a higher-strength tablet than AF 50 Tablet DT and AF 200 Tablet, and lower than AF 400 Tablet. Because of that, it may suit adults who need a larger prescribed dose with fewer tablets, but it is not meant to replace lower strengths for routine starter dosing unless a doctor specifically chooses it. AF 300 Tablet is a standard swallow tablet, unlike the DT and dusting powder forms, which are used differently and for different types of fungal problems.

• Treatment of Candida yeast infections
• Certain mouth, throat, or esophageal fungal infections
• Some vaginal yeast infections when prescribed in tablet form
• Selected skin and systemic fungal infections
• Prevention of fungal infection in higher-risk patients when directed by a doctor

• Swallow AF 300 Tablet whole with water unless your doctor gives different instructions.
• You may take it with or without food.
• Take it at the same time on the scheduled day(s) your prescriber tells you.
• Do not split, crush, or chew the tablet unless a clinician says it is okay.
• If you miss a dose, take it when you remember unless it is close to the next dose; do not double up.
• Use only the amount and schedule prescribed, since AF 300 Tablet is a higher-strength fluconazole tablet.

Each AF 300 Tablet contains 300 mg of fluconazole. Depending on the infection, a doctor may prescribe it as a single dose, once-daily dosing, or a less frequent schedule; the exact frequency and total treatment length depend on the diagnosis and your response. Do not take more tablets in one day than your prescriber has directed, because the right dose for AF 300 Tablet varies by infection and patient factors.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Fluconazole may include:

• Nausea
• Headache
• Stomach pain
• Diarrhea
• Dizziness
• Change in taste
• Mild rash

• AF 300 Tablet is a higher-strength fluconazole tablet, so it should be used only when a clinician has decided this dose is appropriate for your infection.
• Tell your doctor if you have liver disease, kidney disease, heart rhythm problems, or a history of long QT syndrome.
• Fluconazole can interact with many medicines, so your full medication list matters, including prescriptions, OTC products, and supplements.
• Alcohol may worsen stomach upset or strain the liver while you are taking fluconazole.
• Use caution with driving or tasks that need alertness if you feel dizzy after taking AF 300 Tablet.
• Let your clinician know if you are pregnant, trying to become pregnant, or breastfeeding, since fluconazole use may need special review.
• Do not use AF 300 Tablet for an infection unless it was prescribed for that specific condition; fungal symptoms can mimic other illnesses.

• Warfarin and other blood thinners
• Some statins such as simvastatin or atorvastatin
• Certain diabetes medicines that can cause low blood sugar
• Drugs that affect heart rhythm, including some antiarrhythmics
• Some seizure medicines and rifampin

Store AF 300 Tablet in its original strip or box at room temperature, away from moisture, heat, and children.