Glyboral 5 mg Tablet

Glyboral 5 mg Tablet is a prescription diabetes medicine that contains 5 mg of glibenclamide in each tablet. It belongs to the sulfonylurea class, which helps lower blood sugar in adults with type 2 diabetes. Glyboral 5 mg Tablet is used along with diet and exercise to improve blood glucose control when lifestyle measures alone are not enough. This strength is a full-strength tablet and should be used only when a clinician has decided that 5 mg is appropriate.

How it works: Glibenclamide helps the pancreas release more insulin, which lowers the amount of sugar circulating in the blood. In tablet form, Glyboral 5 mg Tablet is swallowed and absorbed through the digestive tract to provide this effect.

Compared with Glyboral 2.5 mg Tablet, Glyboral 5 mg Tablet delivers twice the amount of glibenclamide in each tablet, so it may be chosen when a lower strength is not enough or when a doctor wants a larger dose adjustment. Because it is a higher-strength tablet, the blood sugar-lowering effect may be stronger and the risk of low blood sugar can be greater if it is not matched carefully to meals and other diabetes medicines.

• Type 2 diabetes mellitus
• Improving blood sugar control
• Adjunct to diet and exercise
• May be used with other antidiabetic medicines when prescribed

• Swallow Glyboral 5 mg Tablet whole with water unless your doctor tells you otherwise.
• Take it with or just before your first main meal of the day to reduce the chance of low blood sugar.
• Do not crush or chew the tablet unless a clinician or pharmacist specifically instructs you to.
• If your dose is prescribed more than once daily, space it exactly as directed by your doctor.
• Keep a source of fast sugar with you in case of low blood sugar, especially when starting or changing dose.
• Do not change the timing, dose, or number of tablets on your own.

Each Glyboral 5 mg Tablet provides 5 mg of glibenclamide. The usual number of times per day and the maximum daily dose depend on your blood sugar readings, other medicines, and your doctor’s plan; do not take more than prescribed. Because this is the 5 mg strength, it is often used as a dose step-up rather than a starting tablet for everyone.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Glibenclamide may include:

• Low blood sugar, which may be more noticeable with the 5 mg strength
• Weight gain
• Nausea
• Stomach upset
• Dizziness
• Headache

• Use extra caution if you are older, have irregular meal patterns, or are at higher risk of low blood sugar.
• Do not skip meals after taking Glyboral 5 mg Tablet, because this can trigger hypoglycemia.
• Avoid or limit alcohol, since it can raise the risk of low blood sugar and interfere with diabetes control.
• Tell your doctor if you have kidney, liver, heart, or adrenal problems before starting this medicine.
• Be careful when driving or operating machinery until you know how Glyboral 5 mg Tablet affects you.
• This higher 5 mg strength is not for everyone and should be used only after your prescriber reviews your response to lower doses such as 2.5 mg.
• If you take a beta blocker or certain other medicines, low blood sugar symptoms may be harder to notice.

• Insulin and other diabetes medicines can increase the risk of low blood sugar.
• Alcohol can intensify hypoglycemia risk.
• Certain antibiotics, antifungals, and some blood pressure medicines may change glibenclamide effects.
• Warfarin and other highly protein-bound medicines may interact.
• Corticosteroids and some diuretics may raise blood sugar and reduce the effect of Glyboral 5 mg Tablet.

Store Glyboral 5 mg Tablet at room temperature in its original strip/box, away from moisture and heat, and keep it out of reach of children.