Glyfloz-M 5 mg/500 mg Tablet ER

Glyfloz-M 5 mg/500 mg Tablet ER is a prescription extended-release tablet that combines dapagliflozin 5 mg and metformin 500 mg in each tablet. It belongs to the SGLT2 inhibitor and biguanide medicine classes, and it is used along with diet and exercise to help lower blood sugar in adults with type 2 diabetes. Because it is an ER tablet, the metformin part is released slowly over time to help improve tolerability and provide steadier blood-sugar control. Glyfloz-M 5 mg/500 mg Tablet ER is not for type 1 diabetes or diabetic ketoacidosis.

How it works: Dapagliflozin helps the kidneys remove extra sugar through the urine, which lowers blood glucose. Metformin helps the body use insulin better and reduces sugar made by the liver, while the tablet form allows the metformin to be released slowly.

Glyfloz-M 5 mg/500 mg Tablet ER is a lower-strength combination tablet, so it may be chosen when a doctor wants to start or continue treatment with a modest dapagliflozin dose and a metformin dose that is less likely to cause stomach upset than higher metformin strengths. The extended-release tablet is designed to be swallowed whole and to release metformin gradually, which can make it easier for some patients to take than immediate-release tablets. If your doctor prescribes this exact strength, it is because this 5 mg/500 mg combination fits your blood-sugar plan, kidney function, and tolerability needs.

• Type 2 diabetes blood sugar control
• Use with diet and exercise
• May help lower A1C
• May be used when one medicine alone is not enough
• May be part of a broader diabetes treatment plan

• Swallow Glyfloz-M 5 mg/500 mg Tablet ER whole with water; do not crush, split, or chew it.
• Take it exactly as prescribed, usually once daily if your doctor has chosen this ER strength for you.
• Take it with a meal or as directed to help reduce stomach side effects from metformin.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Drink enough fluids during treatment, especially in hot weather or if you are vomiting or have diarrhea.

Each Glyfloz-M 5 mg/500 mg Tablet ER provides dapagliflozin 5 mg plus metformin 500 mg. Your doctor decides how often to take it, and this strength is commonly used once daily as part of an individualized diabetes plan; the maximum daily amount depends on your total prescribed regimen and kidney function, so follow your prescriber’s directions exactly.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Dapagliflozin + Metformin may include:

• Diarrhea, nausea, or upset stomach
• Gas or abdominal discomfort
• Headache
• Increased urination
• Thirst or dry mouth
• Genital yeast infection or vaginal itching
• Mild low blood sugar if used with insulin or a sulfonylurea

• Do not use Glyfloz-M 5 mg/500 mg Tablet ER if you have type 1 diabetes or diabetic ketoacidosis.
• This exact strength is for adults; it is not a starting choice for everyone and must be tailored by a doctor.
• Tell your doctor if you have kidney disease, liver disease, heart failure, or a history of dehydration.
• Avoid heavy alcohol use, which can raise the risk of lactic acidosis and low blood sugar.
• Because dapagliflozin can increase urination, stay hydrated and use caution if you get dizzy when standing.
• Stop and seek urgent care if you develop vomiting, severe illness, or signs of ketoacidosis.
• If you use insulin or a sulfonylurea, your risk of low blood sugar is higher and you may need monitoring.

• Insulin and sulfonylureas, which can increase the risk of low blood sugar
• Diuretics or water pills, which can worsen dehydration and low blood pressure
• Alcohol, which can raise the risk of lactic acidosis and hypoglycemia
• Iodinated contrast dye used for some scans, which may require temporary stopping of metformin
• Ritonavir, certain HIV medicines, and other drugs that can affect kidney function or glucose control

Store Glyfloz-M 5 mg/500 mg Tablet ER in its original strip/box at room temperature, away from moisture and heat, and keep it out of reach of children.