Azopt Eye Drop 1% (5 mL)

Azopt Eye Drop 1% (5 mL) is a prescription eye drop that contains brinzolamide 1% w/v, which means each drop delivers brinzolamide at the 1% strength. It belongs to the carbonic anhydrase inhibitor class and is used to lower elevated pressure inside the eye. Doctors prescribe Azopt Eye Drop 1% (5 mL) for conditions such as ocular hypertension and open-angle glaucoma. Lowering eye pressure can help reduce the risk of optic nerve damage and vision loss over time.

How it works: Brinzolamide blocks an enzyme in the eye that helps make aqueous fluid, the liquid that keeps eye pressure elevated when too much is produced. By reducing fluid production, Azopt Eye Drop 1% (5 mL) helps lower pressure inside the eye.

Azopt Eye Drop 1% (5 mL) is the standard ophthalmic strength for brinzolamide in this form, so it is designed for patients who need pressure-lowering treatment in the eye rather than a lower-dose or alternate form. Because it is an eye drop, it works locally in the eye and may be chosen when a doctor wants a non-systemic option that can be used on a regular schedule.

• Ocular hypertension
• Open-angle glaucoma
• Lowering increased eye pressure
• Helping protect the optic nerve from pressure damage

• Use only in the eye and exactly as prescribed by your doctor.
• Wash your hands before using Azopt Eye Drop 1% (5 mL).
• Shake the bottle well before each use if directed by the label or prescriber.
• Tilt your head back, pull down the lower eyelid, and place one drop into the affected eye(s).
• Do not let the dropper tip touch your eye, fingers, or any surface.
• If you use other eye medicines, wait at least 5 to 10 minutes between products unless your doctor tells you otherwise.

Azopt Eye Drop 1% (5 mL) provides brinzolamide 1% per drop, and the exact dose is set by your doctor based on your eye pressure and treatment plan. It is commonly used 1 drop in the affected eye(s) 3 times daily, but your prescriber may adjust the schedule; do not use more often than directed. Because this is the 1% strength, it is meant for prescribed maintenance treatment rather than self-directed dose changes.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Brinzolamide may include:

• Temporary blurred vision
• Eye discomfort or burning after instillation
• Bitter or unusual taste in the mouth
• Eye redness
• Dry eyes
• Headache
• Runny nose or throat irritation

• Do not use Azopt Eye Drop 1% (5 mL) if you are allergic to brinzolamide or any sulfonamide medicine unless your doctor specifically says it is safe.
• Tell your doctor if you have kidney problems, because brinzolamide may not be appropriate in some kidney conditions.
• Use caution if you have liver disease or a history of low eye pressure treatment problems.
• Wait before driving or using machines if the drops blur your vision right after use.
• Tell your doctor if you wear soft contact lenses; the preservative may be absorbed by lenses, and you may need to remove them before use.
• Use only as prescribed and do not increase frequency on your own, since more frequent use can raise side effect risk without better results.
• Tell your doctor about all other eye drops you use, because multiple pressure-lowering medicines may need spacing or monitoring.

• Other carbonic anhydrase inhibitors, such as oral acetazolamide or methazolamide
• Other glaucoma eye drops used together without spacing or doctor guidance
• High-dose aspirin or salicylates
• Medicines that may affect kidney function
• Any prescription or over-the-counter product that causes eye irritation or dryness

Store Azopt Eye Drop 1% (5 mL) at room temperature and keep the bottle tightly closed and protected from contamination.