Brivex Eye Drop

Brivex Eye Drop is a prescription eye drop containing brinzolamide and brimonidine in the labeled strength supplied in each bottle. It belongs to the glaucoma/ocular antihypertensive class and is used to lower raised pressure inside the eye. Doctors prescribe Brivex Eye Drop to help treat open-angle glaucoma and ocular hypertension, where reducing eye pressure can help protect vision.

How it works: Brinzolamide lowers eye pressure by reducing the fluid your eye makes, while brimonidine helps both decrease fluid production and improve fluid drainage. As an eye drop, Brivex Eye Drop delivers these medicines directly to the eye to help lower pressure where it is needed.

Brivex Eye Drop is a higher-intensity combination eye medicine intended for people a doctor has already assessed and found to need both ingredients in one drop. Because it is an eye drop rather than a tablet or injection, it acts locally in the eye and may be chosen when separate single-ingredient drops are not enough or when a simpler treatment plan is preferred. The exact labeled strength in each bottle determines how much medicine is delivered per drop, so this product should be used only as directed.

• Open-angle glaucoma
• Ocular hypertension
• Lowering elevated intraocular pressure
• Combination therapy when one eye drop is not enough

• Use Brivex Eye Drop only in the eye as prescribed by your doctor.
• Wash your hands before and after using the bottle.
• Do not let the dropper tip touch your eye, fingers, or any surface.
• If you use other eye medicines, wait at least 5 to 10 minutes between drops unless your doctor tells you otherwise.
• Remove soft contact lenses before using the drops and wait at least 15 minutes before putting them back in.
• Close your eye gently after each drop and press the inner corner of the eye for 1 to 2 minutes to reduce drainage into the nose.

The dose provided by Brivex Eye Drop is the labeled amount of brinzolamide plus brimonidine in each bottle, delivered as eye drops rather than by mouth. It is usually used 1 drop in the affected eye or eyes twice daily, but your doctor may change the schedule based on your eye pressure and response. Do not use more often than prescribed, because the maximum daily amount is set by your prescriber for this exact strength and your condition.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Brinzolamide + Brimonidine may include:

• Eye irritation or burning after instillation
• Blurred vision for a short time after the drop
• Eye redness
• Bitter or unusual taste in the mouth
• Dry mouth
• Headache
• Drowsiness or tiredness

• Brivex Eye Drop can cause temporary blurred vision, so be careful driving or using machinery right after dosing.
• Use extra caution if you have asthma, COPD, severe heart disease, low blood pressure, or a history of fainting.
• Tell your doctor if you have kidney disease, because brinzolamide is a sulfonamide-related medicine and may not be suitable for everyone.
• Alcohol or other medicines that cause drowsiness can worsen sleepiness from brimonidine.
• Do not use this eye drop if you are allergic to brinzolamide, brimonidine, or sulfonamide-type medicines unless your doctor says it is safe.
• Contact lens wearers should remove lenses before dosing and wait before reinserting them.
• Do not share the bottle with anyone else, even if their symptoms seem similar.

• Other glaucoma eye drops unless your doctor coordinates the schedule
• Blood pressure medicines that can add to dizziness or low blood pressure
• CNS depressants such as alcohol, sleeping pills, or opioid pain medicines
• Antidepressants called MAO inhibitors, which can interact with brimonidine
• Sedating antihistamines or anxiety medicines that may increase drowsiness

Store Brivex Eye Drop at room temperature, keep the bottle tightly closed, and protect it from contamination and direct heat.