Combigan Eye Drop 5 mL

Combigan Eye Drop 5 mL is a prescription eye drop that contains brimonidine tartrate and timolol maleate in a 5 mL bottle. It belongs to the anti-glaucoma medicines used to lower pressure inside the eye. Doctors prescribe Combigan Eye Drop 5 mL to help treat open-angle glaucoma or ocular hypertension. By reducing eye pressure, it helps lower the risk of optic nerve damage and vision loss.

How it works: Brimonidine helps your eye make less fluid and also improves fluid drainage, while timolol lowers fluid production in the eye. Together, the two medicines in Combigan Eye Drop 5 mL help reduce pressure inside the eye after the drop is placed on the eye surface.

Combigan Eye Drop 5 mL is a standard multi-dose eye-drop bottle for people who need ongoing pressure control in one or both eyes. Because it combines two medicines in one drop, a doctor may choose it when one medicine alone has not lowered eye pressure enough. There are no other strengths or forms listed for this brand in our store, so this 5 mL eye drop should be used exactly as prescribed by the clinician who evaluated your eye pressure.

• Open-angle glaucoma
• Ocular hypertension
• Lowering elevated eye pressure
• Reducing risk of optic nerve damage

• Wash your hands before using Combigan Eye Drop 5 mL.
• Tilt your head back, pull down the lower eyelid, and place the prescribed number of drops into the affected eye(s).
• Do not let the dropper tip touch your eye, fingers, or any surface.
• If you wear contact lenses, remove them before using the eye drop and wait at least 15 minutes before putting them back in.
• After the drop, close your eye gently and press the inner corner of the eye for 1 to 2 minutes to reduce medicine drainage into the nose.
• Use it at the same times each day, and follow your doctor’s exact schedule rather than changing how often you use it.

Each use of Combigan Eye Drop 5 mL delivers the brimonidine/timolol eye-drop solution from a 5 mL bottle; the exact number of drops per dose is not fixed by the bottle size and depends on your prescription. It is commonly used twice daily, but your doctor may adjust the schedule based on your eye pressure and response. Do not use it more often than prescribed, because extra dosing can raise the chance of side effects and may not improve pressure control.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Brimonidine + Timolol may include:

• Eye burning or stinging after instillation
• Eye redness or irritation
• Blurred vision for a short time after the drop
• Dry mouth
• Headache
• Fatigue or drowsiness
• Watery eyes

• Combigan Eye Drop 5 mL can lower heart rate and blood pressure, so tell your doctor if you have heart disease, low heart rate, or a history of fainting.
• Use caution if you have asthma, COPD, or other breathing problems because timolol can worsen bronchospasm.
• Tell your doctor if you take medicines for depression, blood pressure, diabetes, or heart rhythm problems.
• This eye drop can cause temporary blurred vision or sleepiness, so be careful driving or using machinery after each dose.
• Do not use it if you have had an allergic reaction to brimonidine, timolol, or similar beta-blocker eye drops.
• If you are pregnant or breastfeeding, ask your doctor whether Combigan Eye Drop 5 mL is appropriate for you.
• Contact your doctor before surgery because timolol can affect how some anesthesia and heart medicines work.

• Oral beta-blockers such as metoprolol or propranolol
• Certain antidepressants, especially MAO inhibitors and tricyclics
• Blood pressure medicines that can further slow the heart rate
• Diabetes medicines or insulin, because timolol can mask low blood sugar symptoms
• Other glaucoma eye drops unless your prescriber tells you to use them together

Store Combigan Eye Drop 5 mL tightly closed at room temperature and protect it from contamination; keep the dropper tip clean and do not freeze it.