Natamet 5% 3 mL Eye Drop

Natamet 5% 3 mL Eye Drop is a prescription antifungal eye medicine that contains natamycin 5% in each 3 mL bottle. It belongs to the polyene antifungal class and is used to treat fungal infections of the eye, especially fungal keratitis and other superficial fungal infections of the cornea and conjunctiva. This product is made by Sun Pharmaceutical Industries Ltd. and is supplied as a strip/box of 10 bottles. Natamet 5% 3 mL Eye Drop is meant for use only when a clinician has confirmed or strongly suspected a fungal eye infection.

How it works: Natamycin works by binding to sterols in the fungal cell membrane, which damages the membrane and stops the fungus from growing. As an eye drop, Natamet 5% 3 mL Eye Drop coats the infected surface of the eye so the medicine can act directly where the fungus is causing inflammation and damage.

Natamet 5% 3 mL Eye Drop is a specific high-concentration ophthalmic antifungal formulation, so it is not a general-use eye drop. Compared with oral or non-ocular forms, this eye drop is designed to deliver natamycin directly to the surface of the eye, where the infection is located, which can help your doctor target treatment while limiting body-wide exposure. The 5% strength and 3 mL bottle size are chosen by a clinician based on the type and severity of the fungal infection and how often the medicine needs to be dosed.

• Fungal keratitis
• Fungal conjunctival infection
• Superficial fungal infection of the eye
• Treatment of natamycin-sensitive fungi in the eye

• Wash your hands before using Natamet 5% 3 mL Eye Drop.
• Tilt your head back, pull down the lower eyelid, and place the prescribed number of drops into the eye without touching the dropper tip.
• Close your eyes gently for 1 to 2 minutes after instilling the drop; do not rub the eye.
• If you use other eye medicines, wait at least 5 to 10 minutes between products, unless your doctor tells you otherwise.
• Do not wear contact lenses during an active eye infection unless your eye doctor specifically says it is safe.
• Use it exactly at the times your doctor prescribes, since fungal eye infections often need frequent dosing at first.

Natamet 5% 3 mL Eye Drop provides natamycin 5% in each bottle, and the exact number of drops per dose is determined by your doctor. For fungal eye infections, it may be prescribed several times a day, and the dosing schedule can be frequent at the start and then adjusted as the eye improves. There is no fixed maximum daily dose that applies to every patient; your prescriber decides the safest and most effective schedule for your infection.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Natamycin may include:

• Temporary eye burning or stinging after instillation
• Mild eye irritation or redness
• Blurred vision for a short time after use
• Tearing or watery eyes
• Eye discomfort or itching
• Foreign-body or gritty sensation in the eye

• Use only for confirmed or suspected fungal eye infection; it will not treat bacterial or viral eye disease.
• Do not touch the dropper tip to your eye, fingers, or any surface to avoid contamination.
• If you wear contact lenses, ask your eye doctor when to stop and when it is safe to restart them.
• Vision may be blurred briefly after each dose, so be careful with driving or machinery until your sight clears.
• Tell your doctor if you are pregnant, breastfeeding, or treating a child, because dosing and monitoring may differ.
• Keep using the medicine for the full prescribed course even if the eye feels better early.
• Seek prompt care if pain, light sensitivity, or vision loss worsens, because fungal keratitis can progress quickly.

• Other ophthalmic medicines, including steroid eye drops, may change treatment response and should be spaced apart as directed.
• Other eye drops or ointments can affect how Natamet 5% 3 mL Eye Drop spreads on the eye surface if used too close together.
• Contact lens solutions or lens use can interfere with healing during active infection.
• Topical corticosteroids may worsen some fungal eye infections unless your eye specialist specifically prescribes them with antifungal therapy.

Store Natamet 5% 3 mL Eye Drop in the original container at room temperature, protected from light, and keep the bottle tightly closed when not in use.