Nexpro 40 mg Tablet

Nexpro 40 mg Tablet is a prescription-strength gastro health medicine that contains 40 mg of esomeprazole in each tablet. It belongs to the proton pump inhibitor (PPI) class, which lowers stomach acid. Doctors use Nexpro 40 mg Tablet to treat acid-related conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and stomach or duodenal ulcers.

How it works: Esomeprazole in Nexpro 40 mg Tablet blocks the acid-producing pump in the stomach lining, which reduces the amount of acid released. With less acid, the tablet helps relieve heartburn, allows irritated tissue to heal, and lowers the chance of acid damage.

Nexpro 40 mg Tablet is the higher strength compared with Nexpro 20 mg Tablet, so it is typically chosen when a doctor wants stronger acid suppression or when a lower dose has not been enough. Because this is a 40 mg tablet, it is meant for people a clinician has already assessed; it is not a casual starting option for everyone, and the exact dose depends on the condition being treated.

• GERD and frequent heartburn
• Healing erosive esophagitis
• Short-term treatment of stomach or duodenal ulcers
• Reducing acid in Zollinger-Ellison syndrome
• Prevention of ulcer recurrence when prescribed by a doctor

• Swallow the Nexpro 40 mg Tablet whole with water; do not crush, chew, or split it unless your prescriber specifically tells you otherwise.
• Take it before a meal, usually before breakfast, because PPIs work best when taken before eating.
• If you are prescribed once-daily therapy, try to take the tablet at the same time each day.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Follow your doctor’s directions exactly, especially if you are using Nexpro 40 mg Tablet for an ulcer or severe reflux problem.

Each Nexpro 40 mg Tablet provides 40 mg of esomeprazole. Depending on the condition, it may be taken once daily, and in some cases a doctor may prescribe it more than once daily; the maximum daily dose should be set by the prescriber, not by the patient. This is the higher-strength tablet in this product line, so dosing should be individualized rather than self-chosen.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Esomeprazole may include:

• Headache
• Diarrhea
• Nausea
• Gas
• Stomach pain
• Constipation
• Dizziness

• Tell your doctor if you have liver disease, because Nexpro 40 mg Tablet may need closer monitoring.
• Long-term or high-dose use can increase the risk of low magnesium, vitamin B12 deficiency, and bone fractures.
• Use caution if you take it for a long time, since stomach acid suppression can mask symptoms of more serious conditions.
• Let your prescriber know if you have unexplained weight loss, vomiting, trouble swallowing, or black stools before starting treatment.
• Tell your doctor about all medicines you take, because esomeprazole can change how some drugs are absorbed or metabolized.
• If you are pregnant or breastfeeding, use only if your clinician says the benefits outweigh the risks.
• Do not use this tablet to treat sudden chest pain or symptoms that could be a heart problem.

• Clopidogrel
• Warfarin
• Digoxin
• Atazanavir or nelfinavir
• Methotrexate

Store Nexpro 40 mg Tablet in its original strip or box at room temperature, away from moisture and excess heat.