Apigat 5 Tablet

Apigat 5 Tablet is a prescription anticoagulant tablet that contains apixaban 5 mg in each tablet. It belongs to the direct oral anticoagulant (DOAC) class, which helps prevent and treat harmful blood clots. Apigat 5 Tablet is used to lower the risk of stroke and blood clots in certain people with atrial fibrillation, and to treat or prevent deep vein thrombosis (DVT) and pulmonary embolism (PE).

How it works: Apixaban in Apigat 5 Tablet blocks factor Xa, a clotting protein the body needs to make blood clots. By slowing this step, the tablet helps reduce the chance of forming dangerous clots while still being taken by mouth as a standard film-coated tablet.

Apigat 5 Tablet is the higher-strength tablet in this brand lineup compared with Apigat 2.5 Tablet. It is used when a doctor determines that the 5 mg strength is appropriate for the condition being treated or prevented, rather than the lower-strength tablet. Because apixaban works right after it is absorbed, this tablet begins acting quickly, but the exact dose schedule must be tailored by the prescriber.

• Reduce stroke risk in nonvalvular atrial fibrillation
• Treat deep vein thrombosis (DVT)
• Treat pulmonary embolism (PE)
• Help prevent DVT and PE from coming back
• Prevent blood clots after certain medical situations when prescribed

• Swallow the Apigat 5 Tablet whole with water; do not crush, split, or chew unless your prescriber specifically tells you to.
• Take it exactly at the times prescribed, because missing doses can raise clot risk.
• You may take Apigat 5 Tablet with or without food.
• If you have trouble swallowing tablets, ask your pharmacist or doctor before changing how you take it.
• Do not stop taking this tablet suddenly unless your clinician tells you to, because clot risk can increase.

Each Apigat 5 Tablet contains apixaban 5 mg. The dose is commonly taken twice daily for many approved uses, but the exact schedule depends on why it was prescribed and on your kidney function, age, weight, and other medicines. Your doctor decides the right dose and duration; do not take more than prescribed, and do not change to a different strength on your own.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Apixaban may include:

• Easy bruising
• Nosebleeds
• Bleeding that takes longer to stop
• Nausea
• Minor stomach upset
• Tiredness from mild blood loss

• Apigat 5 Tablet can cause serious bleeding, so get medical advice before any surgery, dental work, or invasive procedure.
• Tell your doctor if you have kidney disease, liver disease, a history of ulcers, or any bleeding disorder.
• Avoid using this tablet with other blood thinners unless your prescriber specifically directs it.
• Limit alcohol, since it can raise bleeding risk and irritate the stomach.
• Use caution if you fall often or do activities with a high injury risk.
• Do not stop Apigat 5 Tablet suddenly without medical guidance, especially if you take it for atrial fibrillation or recent clot treatment.
• If you are pregnant, planning pregnancy, or breastfeeding, discuss risks and benefits with your clinician.

• Aspirin and NSAIDs such as ibuprofen or naproxen can increase bleeding risk.
• Other anticoagulants or antiplatelet medicines can greatly raise bleeding risk.
• Strong CYP3A4/P-gp inhibitors or inducers can change apixaban levels.
• Some herbal products such as St. John’s wort may reduce effectiveness.
• Certain antidepressants, including SSRIs and SNRIs, may increase bleeding tendency.

Store Apigat 5 Tablet in its original strip/box at room temperature, away from moisture, heat, and out of reach of children.