Eptus 50 mg Tablet

Eptus 50 mg Tablet is a prescription tablet that contains 50 mg of eplerenone in each tablet. Eplerenone is a potassium-sparing diuretic, also called an aldosterone antagonist, used to help treat heart failure and high blood pressure in adults. It may also be prescribed after a heart attack in people with reduced heart function, based on a doctor’s assessment. Eptus 50 mg Tablet is one strength of this medicine from Glenmark Pharmaceuticals and is taken by mouth as directed.

How it works: Eplerenone blocks the hormone aldosterone, which tells the body to hold on to salt and water. By reducing this effect, the Eptus 50 mg Tablet helps the body get rid of extra fluid and can lower strain on the heart and blood vessels.

Eptus 50 mg Tablet is the higher tablet strength compared with Eptus 25 mg Tablet, so it is typically chosen when a doctor wants the stronger 50 mg dose rather than starting lower and increasing later. Because this is a higher-strength tablet, it is usually meant for patients who have already been assessed and whose potassium level and kidney function can be monitored. It does not work faster than the 25 mg tablet, but it may reduce the number of tablets needed for a prescribed regimen.

• Heart failure treatment
• High blood pressure management
• After-heart-attack heart protection in selected patients
• Reducing fluid-related strain on the heart

• Swallow the Eptus 50 mg Tablet whole with water; do not crush, chew, or split it unless your doctor says it is okay.
• Take it at the same time each day to help you remember your doses.
• You can take it with or without food unless your prescriber gives different instructions.
• If it upsets your stomach, taking it with a meal may help.
• Follow your doctor’s exact schedule, since the 50 mg strength may be used as part of a step-up dose plan.
• Do not take extra tablets to make up for a missed dose without asking your doctor or pharmacist.

Each Eptus 50 mg Tablet provides 50 mg of eplerenone per tablet. Your doctor decides how often you take it based on why you are taking it, your kidney function, and your blood potassium level; it may be taken once daily or twice daily in some regimens. The total daily dose is limited by the prescribing plan, and your clinician will tell you whether this 50 mg strength is right for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Eplerenone may include:

• Dizziness
• Tiredness
• Diarrhea
• Nausea
• Headache
• High potassium level may occur, especially with the 50 mg strength if kidney function is reduced

• Eptus 50 mg Tablet can raise potassium, so blood tests are important, especially with the higher 50 mg strength.
• Tell your doctor if you have kidney disease, diabetes, or a history of high potassium.
• Avoid potassium supplements and salt substitutes unless your prescriber approves them.
• This tablet may lower blood pressure and cause dizziness, so use caution when driving or standing up quickly.
• Alcohol can worsen dizziness or dehydration.
• Let your doctor know about all heart medicines you take, especially if you have heart failure or have had a recent heart attack.
• Do not use during pregnancy or breastfeeding unless your doctor specifically advises it.

• Potassium supplements or salt substitutes containing potassium
• ACE inhibitors or ARBs such as lisinopril or valsartan
• Strong CYP3A4 inhibitors such as clarithromycin, itraconazole, ketoconazole, or ritonavir
• Certain diuretics or other blood pressure medicines that can affect potassium or kidney function

Store Eptus 50 mg Tablet at room temperature in the original strip or box, away from moisture, heat, and direct light.