Lyvelsa 20 mg Tablet

Lyvelsa 20 mg Tablet is a prescription tablet that contains 20 mg of finerenone in each tablet. It comes in a strip/box of 10 packs and is manufactured by Sun Pharmaceutical Industries Ltd. Finerenone is a nonsteroidal mineralocorticoid receptor antagonist used to help protect the heart and kidneys in people with certain chronic kidney disease or heart-related conditions linked to diabetes and high cardiovascular risk.

How it works: Finerenone blocks mineralocorticoid receptors, which helps reduce harmful hormone-driven inflammation and scarring in the kidneys and heart. As a tablet, Lyvelsa 20 mg Tablet is swallowed whole and delivers the medicine systemically so it can help slow disease progression over time.

Lyvelsa 20 mg Tablet is the higher-strength sibling to Lyvelsa 10 mg Tablet, so it is generally chosen when a doctor wants the 20 mg maintenance strength rather than the lower 10 mg dose. This strength is not usually the starting option for everyone; it may be selected after assessing kidney function, potassium levels, and how well the lower dose was tolerated.

• Chronic kidney disease with type 2 diabetes
• Cardiovascular risk reduction in eligible patients
• Kidney and heart protection in diabetes-related disease
• Doctor-directed long-term maintenance therapy

• Swallow Lyvelsa 20 mg Tablet whole with water; do not chew, crush, or split it unless your doctor or pharmacist says it is safe.
• Take it exactly at the same time each day if your prescriber has set daily dosing.
• It can be taken with or without food unless your doctor gives different instructions.
• If you miss a dose, take it when you remember on the same day; skip it if it is almost time for the next dose.
• Do not take extra tablets to make up for a missed dose.
• Your doctor may adjust the schedule based on blood potassium and kidney test results.

Each Lyvelsa 20 mg Tablet provides 20 mg of finerenone per tablet, and dosing is individualized by the prescriber. It may be taken once daily in many treatment plans, but the exact frequency and maximum daily amount depend on kidney function, potassium levels, and the reason it was prescribed. Do not increase the dose or use it more often than directed by your doctor.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Finerenone may include:

• High potassium (hyperkalemia), which may be more relevant at the 20 mg strength
• Low blood pressure or dizziness
• Weakness or tiredness
• Nausea
• Diarrhea
• Headache

• Lyvelsa 20 mg Tablet is a higher strength and should only be used under careful medical supervision.
• Do not use if you have high potassium unless your doctor specifically says it is safe.
• Your prescriber may order blood tests to monitor potassium and kidney function before and during treatment.
• Tell your doctor about all kidney disease, heart disease, and adrenal problems before starting this tablet.
• Be cautious with alcohol if it worsens dizziness or low blood pressure.
• Avoid driving or standing up quickly if the tablet makes you lightheaded.
• Do not take potassium supplements or salt substitutes unless your doctor approves them.

• Potassium supplements and potassium-containing salt substitutes
• ACE inhibitors and ARBs that can raise potassium
• Strong CYP3A4 inhibitors such as ketoconazole or clarithromycin
• Strong CYP3A4 inducers such as rifampin or carbamazepine
• Other medicines that can affect kidney function or potassium levels

Store Lyvelsa 20 mg Tablet at room temperature in its original strip/box, away from moisture, heat, and direct light.