Sebri 300 mg Tablet

Sebri 300 mg Tablet is an oral prescription medicine that contains 300 mg of irbesartan in each tablet. Irbesartan belongs to the angiotensin II receptor blocker (ARB) class, which is used to treat high blood pressure and to help protect the kidneys in some people with diabetic kidney disease. Sebri 300 mg Tablet is a higher-strength option for patients whose doctor has assessed that 300 mg is appropriate for their treatment plan. By lowering blood pressure, it can also reduce the risk of stroke and other cardiovascular complications over time.

How it works: Irbesartan blocks angiotensin II from tightening blood vessels, so the vessels stay more relaxed and blood can flow more easily. In tablet form, Sebri 300 mg Tablet is swallowed and absorbed through the digestive system, helping provide once-daily blood pressure control for many patients.

Sebri 300 mg Tablet is the full-strength irbesartan tablet form commonly used when a lower tablet strength is not enough to reach the target blood pressure or kidney-protection goal. Because it contains 300 mg in one tablet, it is meant for people who have already been evaluated by a clinician and need this higher dose rather than a smaller starting strength.

• High blood pressure (hypertension)
• Kidney protection in type 2 diabetes with hypertension
• Lowering cardiovascular risk linked to uncontrolled blood pressure
• Long-term blood pressure management prescribed by a doctor

• Swallow Sebri 300 mg Tablet whole with a glass of water; do not crush or chew unless your prescriber tells you otherwise.
• Take it at the same time each day to help you remember your dose.
• It may be taken with or without food.
• If it makes you dizzy, stand up slowly from sitting or lying positions.
• Follow your doctor’s exact instructions; do not change the dose on your own just because this is a 300 mg tablet.

Sebri 300 mg Tablet provides 300 mg of irbesartan in each tablet, which is a higher tablet strength than lower-dose irbesartan tablets. It is often taken once daily, but the exact schedule depends on the condition being treated and your response to therapy; your doctor decides the dose, and the usual maximum is 300 mg per day unless your prescriber directs otherwise.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Irbesartan may include:

• Dizziness, especially when standing up
• Tiredness or fatigue
• Headache
• Upset stomach or nausea
• Diarrhea
• Back pain
• Low blood pressure symptoms may be more noticeable at the 300 mg strength in people sensitive to blood pressure lowering

• Sebri 300 mg Tablet is a higher-strength blood pressure medicine, so it may cause more noticeable dizziness or lightheadedness in some patients.
• Do not use if you are pregnant; irbesartan can harm an unborn baby.
• Use caution if you have kidney disease, liver disease, dehydration, or are on a salt-restricted diet.
• Limit alcohol unless your doctor says it is okay, because alcohol can worsen dizziness and low blood pressure.
• Be careful when driving or using machinery until you know how Sebri 300 mg Tablet affects you.
• Tell your doctor if you have heart failure, a history of angioedema, or very low blood pressure.
• Avoid potassium supplements or salt substitutes unless your clinician approves them.

• Other blood pressure medicines, including diuretics, can increase the blood pressure-lowering effect.
• NSAIDs such as ibuprofen or naproxen may reduce effectiveness and increase kidney risk.
• Potassium supplements or potassium-sparing diuretics can raise potassium too much.
• Lithium levels can increase when taken with irbesartan.
• Aliskiren should generally be avoided in patients with diabetes and may be inappropriate in other patients based on medical history.

Store Sebri 300 mg Tablet in its original strip/box at room temperature, away from moisture, heat, and direct light.