Xarb 300 Tablet

Xarb 300 Tablet is a prescription tablet containing irbesartan 300 mg in each tablet. It belongs to a group of medicines called angiotensin II receptor blockers (ARBs), which are used to treat high blood pressure and to help protect the kidneys in some people with type 2 diabetes and kidney disease. Xarb 300 Tablet may also be used as part of a treatment plan to lower the risk of stroke or other heart and blood vessel complications related to high blood pressure. Because this is the 300 mg strength, it is a higher-strength irbesartan tablet chosen when a clinician determines that a lower dose is not enough or is not appropriate.

How it works: Irbesartan in Xarb 300 Tablet blocks the action of angiotensin II, a natural substance that tightens blood vessels. By relaxing blood vessels, this tablet helps blood flow more easily and lowers blood pressure.

Xarb 300 Tablet is the higher-strength irbesartan tablet, so it is not usually the first dose for everyone. A doctor may choose Xarb 300 Tablet for people who have already been assessed and need this full-strength tablet for blood pressure control or kidney protection, rather than a lower-strength irbesartan option. Since there are no other strengths or forms of this brand listed here, Xarb 300 Tablet represents the full labeled strength available for this product.

• High blood pressure
• Kidney protection in type 2 diabetes with protein in the urine
• Blood pressure control to reduce cardiovascular risk
• Part of a doctor-directed long-term blood pressure plan

• Swallow Xarb 300 Tablet whole with a glass of water.
• Take it at the same time each day so your blood pressure control stays steady.
• You can take it with or without food.
• Do not crush or chew the tablet unless your prescriber or pharmacist tells you otherwise.
• If you miss a dose, take it when you remember unless it is almost time for the next dose; do not double up.
• Stand up slowly after taking it, especially when you first start, because dizziness can happen.

Each Xarb 300 Tablet provides irbesartan 300 mg. This is the labeled strength per tablet, and the exact schedule depends on why it is prescribed and how you respond to treatment; it may be taken once daily if your doctor prescribes it that way. Do not change the dose or take more than directed by your doctor; the maximum daily amount for adults is typically 300 mg per day for this medicine when used for blood pressure or diabetic kidney disease.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Irbesartan may include:

• Dizziness, which may be more noticeable with the 300 mg strength
• Tiredness
• Lightheadedness when standing up
• Nausea
• Diarrhea
• Back pain
• Muscle aches

• Xarb 300 Tablet can cause low blood pressure, especially if you are dehydrated or already taking a diuretic.
• Do not use this medicine during pregnancy; it can harm an unborn baby.
• People with kidney disease, liver disease, or dehydration need careful monitoring with this 300 mg tablet.
• Avoid potassium supplements and salt substitutes unless your clinician says they are safe.
• Alcohol can increase dizziness or lightheadedness with irbesartan.
• Be careful driving or using machinery until you know how Xarb 300 Tablet affects you.
• Tell your doctor if you have a history of heart failure, severe vomiting, diarrhea, or low blood pressure.

• Potassium supplements or potassium-containing salt substitutes
• Diuretics such as water pills
• NSAIDs like ibuprofen or naproxen
• Lithium
• Other blood pressure medicines that may further lower blood pressure

Store Xarb 300 Tablet at room temperature in a dry place, and keep the tablets in their original strip/box away from excess heat and moisture.