Gestone 8% Vaginal gel

Gestone 8% Vaginal gel is a progesterone medicine in gel form used to support the uterine lining and help treat hormone-related fertility problems. Each tube contains progesterone 8%, giving a concentrated vaginal dose that is absorbed through the vaginal tissue. It belongs to the progestogen (progesterone) class and is commonly used in infertility therapy, including luteal phase support in assisted reproductive treatment. Gestone 8% Vaginal gel is prescribed by a clinician when progesterone supplementation is needed after evaluation.

How it works: Progesterone helps prepare the uterus and keep the lining stable so an embryo can implant and early pregnancy support can continue. As a vaginal gel, Gestone 8% Vaginal gel places progesterone close to the reproductive tissues, where it is absorbed directly into the body.

Gestone 8% Vaginal gel is a higher-concentration vaginal progesterone product, so each tube delivers more progesterone than lower-strength gel or cream options. That can make it useful when a doctor wants a specific vaginal progesterone dose with local absorption and less frequent application, but it is not something to start on your own. A prescriber may choose Gestone 8% Vaginal gel based on your fertility treatment plan, hormone levels, and how well you tolerate other progesterone forms.

• Luteal phase support in infertility treatment
• Progesterone supplementation during assisted reproduction
• Support of the uterine lining after ovulation procedures
• Treatment of progesterone deficiency when prescribed by a doctor

• Use Gestone 8% Vaginal gel exactly as your doctor directs; the amount and schedule are individualized.
• Apply it vaginally, not by mouth, and do not swallow the gel.
• Use it at the same time each day if your doctor prescribes regular dosing.
• Wash your hands before and after use and follow the package instructions for the applicator or tube.
• Avoid douching or inserting other vaginal products right before or after use unless your doctor says it is okay.
• If your clinician advises timing around intercourse or procedures, follow that timing closely.

Each tube of Gestone 8% Vaginal gel contains progesterone 8%, which is a concentrated vaginal dose. Some patients may use it once daily, while others may need more frequent dosing depending on the fertility protocol; the maximum number of tubes per day should be set by the prescribing doctor. Do not change the dose or stop early unless your clinician tells you to.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Progesterone may include:

• Vaginal discharge or leakage after application
• Vaginal irritation or burning
• Bloating or abdominal discomfort
• Breast tenderness
• Headache
• Drowsiness or fatigue

• Use only if your doctor has confirmed that progesterone support is appropriate for you
• This 8% strength is concentrated, so do not use more tubes or more often than prescribed
• Tell your doctor if you have a history of blood clots, stroke, liver disease, breast cancer, or unexplained vaginal bleeding
• Use caution if you feel sleepy or dizzy after applying the gel, especially when driving
• Report severe pelvic pain, heavy bleeding, or signs of pregnancy complications right away
• Tell your prescriber about all vaginal products you use, since they may interfere with absorption or application
• Avoid alcohol if it worsens dizziness or drowsiness while you are using progesterone

• Other progesterone or hormone medicines
• Blood thinners such as warfarin
• Medicines that may affect liver enzymes, including some antiseizure drugs and rifampin
• Some herbal products, especially St. John’s wort
• Other vaginal medications or products that may change absorption

Store Gestone 8% Vaginal gel at room temperature in the original strip/box of 10 tubes, away from heat, moisture, and direct light.