Susten 8% Vaginal gel

Susten 8% Vaginal gel is a progesterone medicine in gel form used for vaginal administration. Each tube contains progesterone 8%, and it belongs to the progestin class of hormones. It is commonly used in fertility care and to support the uterine lining when progesterone levels need to be supplemented. This strength is intended for use exactly as prescribed by a clinician familiar with your treatment plan.

How it works: Progesterone helps prepare and maintain the uterine lining so it is more supportive for implantation and early pregnancy support when prescribed for fertility treatment. The gel form is placed in the vagina so the medicine can be absorbed through the vaginal tissues and delivered close to the uterus.

Susten 8% Vaginal gel is a higher-strength progesterone vaginal gel, so it is chosen when a doctor wants stronger local progesterone support than a lower-strength option would provide. Compared with lower strengths, the 8% gel can deliver a more concentrated dose in the same gel volume, which may be helpful in assisted reproduction or other progesterone-support regimens. Its vaginal form is designed to act locally while still providing systemic progesterone absorption.

• Luteal phase support in fertility treatment
• Support after assisted reproductive procedures
• Progesterone supplementation when prescribed
• Help maintain the uterine lining

• Use Susten 8% Vaginal gel only as directed by your doctor; this is not an oral medicine.
• Insert the full contents of the tube into the vagina using the applicator or method provided with the package.
• Try to use it at the same time each day to keep progesterone levels steady.
• Wash your hands before and after use.
• If leakage occurs, wear a panty liner; the medicine may leave discharge.
• Do not swallow the gel or use it for a purpose other than vaginal insertion.

Each tube of Susten 8% Vaginal gel provides progesterone 8%, which is a concentrated vaginal strength. The exact dosing schedule may vary by indication, and your doctor may prescribe it once daily or more than once daily depending on your fertility protocol. Do not use more than the amount your clinician prescribes, because the maximum daily dose is individualized for your treatment plan.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Progesterone may include:

• Vaginal discharge or leakage
• Vaginal irritation or burning
• Bloating
• Breast tenderness
• Headache
• Drowsiness or fatigue

• Use extra caution if you have a history of blood clots, stroke, or hormone-sensitive cancer.
• Tell your doctor if you have liver disease, migraine, asthma, epilepsy, or heart disease.
• Avoid using other vaginal products unless your clinician says they are okay, since they may affect absorption.
• This gel may cause drowsiness or dizziness in some people, so be careful with driving until you know how it affects you.
• Alcohol can worsen dizziness or sleepiness if the medicine affects you that way.
• Use during pregnancy or breastfeeding only if your doctor specifically tells you to do so.
• If you have unexplained vaginal bleeding, report it before starting or continuing treatment.

• Other hormone medicines, including estrogen or additional progesterone products
• Rifampin and other medicines that can change hormone metabolism
• Certain anti-seizure medicines such as carbamazepine or phenytoin
• Some antifungal or antibiotic therapies that may alter absorption or metabolism
• Other vaginal medications or products used at the same time

Store Susten 8% Vaginal gel at room temperature in the original strip/box of 10 tubes, away from excess heat and moisture.