Duzela 40 mg Capsule

Duzela 40 mg Capsule contains 40 mg of duloxetine in each capsule. Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for conditions such as depression, anxiety, nerve pain, and certain pain-related disorders, depending on a doctor’s assessment. This Duzela 40 mg Capsule is the middle strength in the range we carry, so it may be chosen when a prescriber wants more than the lower 20 mg or 30 mg capsules but does not want to move straight to the 60 mg capsule.

How it works: Duloxetine works by increasing the amount of serotonin and norepinephrine available in the brain and spinal cord, which can help improve mood and reduce certain pain signals. In capsule form, Duzela 40 mg is swallowed whole so the medicine can be absorbed and released properly in the body.

Duzela 40 mg Capsule is a middle-strength option, sitting between the lower 20 mg and 30 mg capsules and the higher 60 mg capsule. A doctor may choose this strength when a patient needs a dose adjustment that is more gradual than jumping to 60 mg, or when the 40 mg capsule better matches the prescribed daily amount.

• Depression
• Generalized anxiety disorder
• Diabetic nerve pain
• Fibromyalgia pain
• Chronic musculoskeletal pain

• Swallow Duzela 40 mg Capsule whole with water; do not open, crush, chew, or split it.
• Take it at the same time each day to help you remember doses.
• It may be taken with or without food, but taking it with food may help if it upsets your stomach.
• If it makes you sleepy or dizzy, avoid driving until you know how it affects you.
• Do not stop Duzela 40 mg Capsule suddenly unless your doctor tells you to, because withdrawal symptoms can occur.
• If you miss a dose, take it when you remember unless it is close to the next dose; do not double up.

Each Duzela 40 mg Capsule provides 40 mg of duloxetine. Depending on the condition being treated, a doctor may prescribe it once daily, or in some cases divided doses, but the exact schedule is individualized and should not be self-chosen. The total daily dose is determined by the prescriber, and higher daily amounts are only used when clinically appropriate.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Duloxetine may include:

• Nausea
• Dry mouth
• Sleepiness or fatigue
• Dizziness
• Constipation
• Loss of appetite
• Increased sweating

• Duzela 40 mg Capsule is a prescription medicine and should only be used if a clinician has assessed you for the right dose.
• Avoid alcohol or use it only if your doctor says it is safe, because both can increase liver and nervous system risks.
• Tell your doctor if you have liver disease, kidney disease, glaucoma, high blood pressure, or a seizure history.
• Use caution when driving or doing tasks that need alertness, especially when starting Duzela 40 mg Capsule or after a dose change.
• Do not take it with MAO inhibitors, or within the required washout period, because dangerous reactions can occur.
• Tell your doctor if you take blood thinners or other medicines that can increase bleeding risk.
• Do not stop the capsule suddenly, because dizziness, irritability, nausea, and other discontinuation symptoms can happen.

• MAO inhibitors such as phenelzine or linezolid
• Other serotonergic medicines such as SSRIs, SNRIs, triptans, tramadol, or St. John’s wort
• Blood thinners and antiplatelet drugs such as warfarin, aspirin, or clopidogrel
• NSAIDs such as ibuprofen or naproxen, which may raise bleeding risk

Store Duzela 40 mg Capsule at room temperature in a dry place, away from heat, moisture, and direct light, and keep it in the original strip/box of 10 capsules.