Cleft 10 Tablet

Cleft 10 Tablet is a prescription tablet containing leflunomide, with 10 mg in each tablet as labelled. It belongs to the disease-modifying antirheumatic drug (DMARD) class and is used to help manage autoimmune inflammation, especially rheumatoid arthritis. Cleft 10 Tablet works by slowing overactive immune activity that can damage joints. It is not a pain reliever that works immediately; its benefit comes from reducing the underlying inflammation over time.

How it works: Leflunomide in Cleft 10 Tablet lowers the activity of immune cells that drive inflammation in the joints. This tablet form is swallowed and absorbed through the stomach and intestines so the medicine can work throughout the body.

Cleft 10 Tablet is the 10 mg strength, which is a lower-dose tablet that may be chosen when a doctor wants a gentler starting point or a maintenance dose. Because there are no other strengths or forms listed for this brand, Cleft 10 Tablet fits standard leflunomide dosing as one tablet that can be adjusted by the prescriber based on response and tolerability.

• Rheumatoid arthritis
• Reducing joint swelling and pain from inflammatory arthritis
• Slowing joint damage caused by autoimmune disease
• Long-term control of symptoms when prescribed by a doctor

• Swallow Cleft 10 Tablet whole with water; do not crush, split, or chew unless your doctor specifically tells you to.
• Take it at the same time each day to help you remember your doses.
• You may take it with or without food.
• If your stomach feels upset, taking the tablet with food may help.
• Do not take extra tablets to make up for a missed dose unless your prescriber tells you to do so.
• Because leflunomide stays in the body for a long time, follow your doctor’s instructions exactly and do not stop it on your own.

Each Cleft 10 Tablet provides 10 mg of leflunomide per tablet. Your doctor may prescribe it once daily, but the exact schedule and whether a higher or lower dose is needed depend on your condition, lab results, and how well you tolerate treatment. Do not exceed the amount your prescriber recommends; the maximum daily dose is set by the doctor for your individual treatment plan.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Leflunomide may include:

• Diarrhea
• Nausea
• Headache
• Hair thinning or hair loss
• Upset stomach
• Raised liver tests
• Feeling tired

• Cleft 10 Tablet can harm an unborn baby; it is not safe in pregnancy unless a specialist has specifically directed otherwise.
• Do not use it if you have active liver disease or significant liver problems unless your doctor says it is appropriate.
• Alcohol can increase the risk of liver damage, so ask your doctor before drinking.
• Your doctor may order blood tests to monitor liver function and blood counts during treatment.
• Tell your clinician if you have a history of serious infection, tuberculosis, or weak immune system.
• Use caution with driving if you feel dizzy, weak, or unwell after taking Cleft 10 Tablet.
• Do not share this medicine with anyone else, even if they have similar symptoms.

• Methotrexate
• Warfarin and other blood thinners
• Live vaccines
• Other medicines that can affect the liver, such as some antibiotics, antifungals, or statins
• Cholestyramine or activated charcoal, which can reduce leflunomide levels and may be used in special situations

Store Cleft 10 Tablet in its original strip or box at room temperature, away from excess heat, moisture, and direct light.