Lefra 10 Tablet

Lefra 10 Tablet is a prescription tablet that contains leflunomide 10 mg in each tablet. It belongs to a disease-modifying antirheumatic drug (DMARD) class and is used to treat active rheumatoid arthritis in adults. Lefra 10 Tablet helps reduce inflammation, joint pain, and swelling, and it may also help slow joint damage over time. This is not a quick pain reliever; it is taken regularly as directed by a doctor.

How it works: Leflunomide in Lefra 10 Tablet works by lowering the activity of immune cells that drive inflammation in rheumatoid arthritis. By dampening this overactive immune response, the tablet can help ease swelling, pain, and stiffness in the joints.

Lefra 10 Tablet is the lower-strength tablet in this product line, which can be useful when a doctor wants a gentler starting dose, a dose reduction, or a maintenance dose for certain patients. Compared with higher-strength leflunomide tablets, the 10 mg tablet gives more flexibility for careful dose adjustment and may be better tolerated in some people.

• Rheumatoid arthritis
• Reduction of joint swelling and stiffness
• Help slow progression of joint damage
• Long-term anti-inflammatory treatment

• Swallow Lefra 10 Tablet whole with water; do not crush, chew, or split unless your doctor specifically tells you to.
• Take it at the same time each day to help you remember.
• You may take it with or without food; food may help if it upsets your stomach.
• Follow the exact schedule your doctor prescribes, because leflunomide dosing is individualized.
• Do not take extra tablets to make up for a missed dose unless your prescriber tells you to do so.

Each Lefra 10 Tablet provides 10 mg of leflunomide per tablet. The dose may be taken once daily, but the exact schedule and whether a higher or lower amount is needed depend on your doctor’s plan and how you respond. Do not change the dose on your own, and do not exceed the daily amount prescribed by your clinician.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Leflunomide may include:

• Diarrhea
• Nausea
• Headache
• Hair thinning or hair loss
• Increased blood pressure
• Abdominal pain
• Rash

• Lefra 10 Tablet can harm an unborn baby, so pregnancy must be avoided during treatment and for as long as your doctor advises afterward.
• Women who could become pregnant and some men may need a washout plan before pregnancy; follow your prescriber’s instructions exactly.
• This medicine can affect the liver, so avoid heavy alcohol use and keep all lab appointments for liver tests.
• Tell your doctor if you have liver disease, kidney disease, a history of serious infection, or high blood pressure.
• Because dizziness or headache can occur, use caution when driving or doing tasks that need alertness until you know how the tablet affects you.
• Do not start Lefra 10 Tablet if you have an active infection without checking with your doctor first.
• Do not receive live vaccines unless your healthcare professional says it is safe.

• Warfarin and other blood thinners
• Methotrexate or other medicines that can affect the liver
• Rifampin
• Cholestyramine or activated charcoal, which can lower leflunomide levels
• Other immunosuppressive medicines

Store Lefra 10 Tablet in its original strip or box at room temperature, away from moisture and out of reach of children.