Valodex 20 mg Tablet

Valodex 20 mg Tablet is a prescription anti-cancer medicine containing tamoxifen 20 mg in each tablet. This pack contains Valodex 20 mg Tablet in a strip/box of 10 packs, and each tablet delivers the full 20 mg strength. Tamoxifen belongs to the selective estrogen receptor modulator (SERM) class and is used in the treatment and risk reduction of certain hormone-sensitive breast cancers. It may also be prescribed for other doctor-directed breast cancer uses based on your condition.

How it works: Tamoxifen works by blocking estrogen from attaching to estrogen receptors in breast tissue, which can slow or stop the growth of hormone-sensitive cancer cells. As a tablet, Valodex 20 mg Tablet is taken by mouth and releases tamoxifen for absorption into the body, where it helps control estrogen-driven cancer activity.

Valodex 20 mg Tablet is the higher-strength option compared with Valodex 10 mg Tablet, so it is usually chosen when a clinician wants a full 20 mg dose in a single tablet. Because this is not a starting dose for everyone, it is typically used only after a doctor has assessed the diagnosis, treatment plan, and how you tolerate tamoxifen. Some patients may notice the effects and side effects of tamoxifen more clearly at this strength simply because each tablet provides the complete 20 mg dose.

• Treatment of hormone receptor-positive breast cancer
• Reducing the risk of breast cancer recurrence
• Lowering the risk of breast cancer in selected high-risk patients
• Doctor-directed treatment for certain breast cancer settings

• Swallow Valodex 20 mg Tablet whole with water; do not crush or chew it unless your doctor specifically tells you to.
• Take it at the same time each day to help you remember your doses.
• You may take it with or without food.
• If it upsets your stomach, taking it after a meal may help.
• Do not take extra tablets to make up for a missed dose unless your prescriber advises you to.
• Follow the exact schedule from your oncology team, since tamoxifen dosing can vary by treatment plan.

Each Valodex 20 mg Tablet provides 20 mg of tamoxifen per tablet, which is the standard full tablet strength many adults are prescribed. It is often taken once daily, but the exact frequency and duration depend on the cancer type, treatment goal, and your doctor’s plan. Do not exceed the dose prescribed by your clinician; your doctor decides whether 20 mg once daily or another regimen is appropriate for you.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Tamoxifen may include:

• Hot flashes
• Nausea
• Tiredness
• Headache
• Mood changes
• Vaginal discharge or menstrual changes
• Leg cramps or joint pain

• Valodex 20 mg Tablet is a higher-strength tamoxifen tablet, so use it only under close medical supervision.
• Tell your doctor if you have a history of blood clots, stroke, or conditions that increase clot risk.
• Use caution if you have liver disease, because tamoxifen is processed by the liver.
• Report any abnormal vaginal bleeding right away, especially if you are premenopausal or postmenopausal.
• This medicine may affect fertility and menstrual cycles; discuss pregnancy prevention with your doctor.
• Do not use if you are pregnant, and avoid breastfeeding unless your prescriber says otherwise.
• If you feel dizzy, tired, or unwell after taking it, be careful driving or operating machinery until you know how it affects you.

• Warfarin and other blood thinners
• Strong CYP2D6 inhibitors such as paroxetine or fluoxetine, which may reduce tamoxifen activation
• Rifampin and other enzyme-inducing medicines
• Certain hormonal therapies or estrogen-containing products
• Some chemotherapy or cancer medicines, depending on the regimen

Store Valodex 20 mg Tablet at room temperature in its original strip/box, away from moisture, heat, and direct light.