Dicorate ER 500 mg Tablet

Dicorate ER 500 mg Tablet is an extended-release tablet of divalproex, with each tablet containing 500 mg of the active ingredient. It belongs to the anticonvulsant and mood-stabilizing drug family, and it is used in migraine prevention as part of the anti-migraine category. This product is the 500 mg tablet strength made by Sun Pharmaceutical Industries Ltd., supplied in a strip/box of 10 tablets. It is not for treating an active migraine attack; it is used on a regular schedule to help lower migraine frequency.

How it works: Divalproex helps calm overactive nerve activity in the brain by increasing the effect of a natural calming chemical called GABA. In Dicorate ER 500 mg Tablet, the extended-release tablet lets the medicine leave the tablet gradually, which helps maintain more even medicine levels through the day.

Dicorate ER 500 mg Tablet is a mid-to-higher strength option compared with Dicorate ER 125 mg Tablet and Dicorate ER 250 mg Tablet, so it is typically chosen when a doctor wants fewer tablets to reach a prescribed daily dose. Because it is an ER tablet, it releases divalproex slowly over time, which may help provide steadier blood levels than immediate-release forms. A clinician may prefer this strength for patients who have already been assessed and need a dose that fits their ongoing prevention plan.

• Migraine prevention
• Reduction of migraine frequency
• Ongoing preventive therapy for patients selected by a doctor
• Divalproex-based maintenance treatment

• Swallow Dicorate ER 500 mg Tablet whole with water; do not crush, split, or chew the extended-release tablet.
• Take it exactly as prescribed, at the same time each day if possible.
• It may be taken with or without food; taking it with food can help reduce stomach upset.
• Do not change from Dicorate ER 500 mg Tablet to another divalproex product without your doctor’s guidance.
• If you miss a dose, take it when you remember unless it is close to the next dose; do not double up.
• Avoid alcohol unless your prescriber says it is safe, because it can increase drowsiness and other side effects.

Dicorate ER 500 mg Tablet provides 500 mg of divalproex in each tablet, so a doctor may prescribe one tablet or more tablets per day depending on the target dose. The exact frequency can vary from once daily to divided dosing, and the maximum daily amount is individualized by the prescriber based on response and safety monitoring. Do not self-adjust the dose, because this higher-strength tablet should be used only in the dose your doctor has specifically chosen.

Do not change your dose or stop the medicine without speaking to your doctor.

Common side effects of Divalproex may include:

• Nausea
• Sleepiness or drowsiness
• Dizziness
• Tremor
• Stomach pain or indigestion
• Weight gain
• Hair thinning

• Dicorate ER 500 mg Tablet is a higher-strength tablet and should be used only under close medical supervision.
• Do not use during pregnancy unless your doctor has determined it is necessary; divalproex can seriously harm an unborn baby.
• Tell your doctor if you have liver disease, a history of pancreatitis, or a bleeding disorder before taking this medicine.
• This medicine can cause drowsiness, so use caution when driving or operating machinery until you know how it affects you.
• Avoid alcohol because it can worsen sleepiness and increase the risk of side effects.
• Older adults and people taking multiple seizure or migraine medicines may need closer monitoring.
• Do not stop the tablet suddenly without medical advice, as stopping abruptly can cause problems.

• Aspirin and other blood thinners can increase bleeding risk.
• Other medicines that cause drowsiness, including sedatives, opioids, and some sleep medicines, can add to sleepiness.
• Topiramate may increase the risk of certain serious side effects when used with divalproex.
• Some antibiotics and other medicines can change divalproex levels, so your prescriber should review all medications and supplements.

Store Dicorate ER 500 mg Tablet at room temperature in the original strip, away from moisture, heat, and direct light, and keep it out of reach of children.